M7694

Mupirocin

≥92% (HPLC), powder

• Sinónimos: 5,9-Anhydro-2,3,4,8-tetradeoxy-8-[[3-(2-hydroxy-1-methylpropyl)oxiranyl]methyl]-3-methyl-[2E,8[2S,3S(1S,2S)]]-L-talonon-2-enonic acid 8-carboxyoctyl ester, BRL 4910A, Pseudomonic acid
• Fórmula empírica (notación de Hill): C₂₆H₄₄O₉
• Número de CAS: 12650-69-0
• Peso molecular: 500.62
• Número MDL: MFCD01711620
• Código UNSPSC: 12352200
• ID de la sustancia en PubChem: 24724542
• NACRES: NA.77

Propiedades

• Nivel de calidad: 100
• Ensayo: ≥92% (HPLC)
• Formulario: powder
• actividad óptica: [α]/D -15.7 to -20°, c = 1 in methanol
• color: white to tan
• solubilidad: DMSO: ≥10 mg/mL
• espectro de actividad antibiótica: fungi
• Modo de acción: enzyme | inhibits; protein synthesis | interferes
• emisor: GlaxoSmithKline
• temp. de almacenamiento: room temp
• cadena SMILES: [H][C@@]1(CO[C@@H](C\C(C)=C\C(=O)OCCCCCCCCC(O)=O)[C@H](O)[C@@H]1O)C[C@@H]2O[C@@]2([H])[C@@H](C)[C@H](C)O
• InChI: 1S/C26H44O9/c1-16(13-23(30)33-11-9-7-5-4-6-8-10-22(28)29)12-20-25(32)24(31)19(15-34-20)14-21-26(35-21)17(2)18(3)27/h13,17-21,24-27,31-32H,4-12,14-15H2,1-3H3,(H,28,29)/b16-13+/t17-,18-,19-,20-,21-,24+,25-,26-/m0/s1
• Clave InChI: MINDHVHHQZYEEK-HBBNESRFSA-N

Descripción

Descripción general

Mupirocin is produced by Pseudomonas fluorescens. Mupirocin is used to treat impetigo and skin infections.

Aplicación

Mupirocin has been used:

• for kinetic assay
• to assess its resistance by performing turbidity assay
• to determine its antimicrobial susceptibility

Acciones bioquímicas o fisiológicas

Antibiotic; inhibits isoleucyl-tRNA synthetase (IRS).

Características y beneficios

This compound was developed by GlaxoSmithKline. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Nota de preparación

Mupirocin is poorly soluble in water (26 mg/L), but highly soluble in DMSO (≥10 mg/mL). If sterilization is required, it is advisable to use filter sterilization with a 0.22 µm PTFE, Polypropylene, or Nylon filter membrane.

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 2
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable
• Equipo de protección personal: Eyeshields, Gloves, type N95 (US)