M5793

3-Morpholinosydnonimine hydrochloride

(consistent with structure, NMR)

• Sinónimos: 3-(4-Morpholinyl)sydnone imine hydrochloride, Linsidomine hydrochloride, SIN-1 hydrochloride
• Fórmula empírica (notación de Hill): C₆H₁₀N₄O₂ · HCl
• Número de CAS: 16142-27-1
• Peso molecular: 206.63
• MDL number: MFCD00214332
• UNSPSC Code: 12352200
• PubChem Substance ID: 24897048
• NACRES: NA.77

Propiedades

• Quality Level: 200
• storage temp.: −20°C
• SMILES string: Cl[H].[NH-]c1c[n+](no1)N2CCOCC2
• InChI: 1S/C6H10N4O2.ClH/c7-6-5-10(8-12-6)9-1-3-11-4-2-9;/h5,7H,1-4H2;1H
• InChI key: NCGICGYLBXGBGN-UHFFFAOYSA-N

Descripción

Application

3-Morpholinosydnonimine hydrochloride has been used:

• as a peroxynitrite donor standard to study the accumulation of peroxynitrite in Arabidopsis thaliana
• to study its effects on nitrosative stress in human brain vascular pericytes and human embryonic kidney cells
• as a ROS to study its effects on mouse embryonic fibroblasts

Biochem/physiol Actions

3-Morpholinosydnonimine participates in the inhibition of cysteine proteases.

Liberates nitric oxide (NO) spontaneously when in solution, activating guanylyl cyclase and causing an increase in cyclic-GMP. This product is a vasodilator and inhibits platelet aggregation. Using molecular oxygen, it generates both superoxide anion and nitric oxide that spontaneously form peroxynitrite.

Información de seguridad

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 2
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)