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Key Documents

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M5651

Supelco

Mepenzolate bromide

analytical standard

Sinónimos:

3-Hydroxy-1,1-dimethylpiperidinium bromide benzilate

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About This Item

Fórmula lineal:
C21H26NO3Br
Número de CAS:
76-90-4
Peso molecular:
420.34
EC Number:
200-992-7
MDL number:
MFCD00079450
UNSPSC Code:
41116107
PubChem Substance ID:
329818020
NACRES:
NA.24

grade

analytical standard

Quality Level

200

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)
veterinary

format

neat

SMILES string

Br.C[N]1(C)CCCC(C1)OC(=O)C(O)(c2ccccc2)c3ccccc3

InChI

1S/C21H26NO3.BrH/c1-22(2)15-9-14-19(16-22)25-20(23)21(24,17-10-5-3-6-11-17)18-12-7-4-8-13-18;/h3-8,10-13,19,24H,9,14-16H2,1-2H3;1H

InChI key

FOPUTUUUOOOXQU-UHFFFAOYSA-N

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Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H302

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Certificados de análisis (COA)

Lot/Batch Number
0000253441
0000274807
0000286744
097F0944

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C S Tsai et al.
Research communications in chemical pathology and pharmacology, 55(2), 275-278 (1987-02-01)
The responsiveness of the cholinergic receptor (ChR) of the longitudinal muscle of guinea-pig isolated ileum was characterized by determining the ED50 of acetylcholine (ACh) and pA2 of mepenzolate (MPZ) in tissues from animals of different ages. The ages of guinea
Y Sudo et al.
Neurology, 51(5), 1297-1302 (1998-11-18)
To investigate the function of the muscarinic cholinergic receptor (mAchR) in narcolepsy and the effects of pharmacotherapy on mAchRs. Muscarinic neural transmission serves as the main executive system in REM sleep. Studies in canine narcolepsy reported an increase in mAchRs
R F Ochillo et al.
Research communications in chemical pathology and pharmacology, 36(3), 503-506 (1982-06-01)
The mydriatic effects of mepenzolate, a quarternary antimuscarinic agent, has been investigated and compared with those of atropine by pupillographic analysis in rabbits. The time-response curve for the onset of action for the agents (half-time, ca.5 min) was the same
M Cohen-Armon et al.
Journal of cardiovascular pharmacology, 6(6), 1148-1155 (1984-11-01)
The possible interaction between the muscarinic receptor and the antiarrythmic drug amiodarone was studied physiologically in the guinea pig ileum, as well as by competition binding experiments in rat brain and cardiac tissues, using the highly specific tritiated muscarinic antagonist
G R Murray et al.
Journal of chromatography, 308, 143-151 (1984-06-08)
A new sensitive and selective capillary column gas chromatographic method for the anti-cholinergic agent glycopyrronium bromide in human plasma is described. The procedure involves preliminary ion-pair extraction of the drug into dichloromethane, followed by concentration and analysis of the ion-pair
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