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M1778

Sigma-Aldrich

Mucina from porcine stomach

Type III, bound sialic acid 0.5-1.5 %, partially purified powder

Sinónimos:

MUC

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About This Item

Número de CAS:
84082-64-4
EC Number:
282-010-7
MDL number:
MFCD00131629
UNSPSC Code:
12352202
NACRES:
NA.61

biological source

Porcine stomach

Quality Level

200

type

Type III

form

partially purified powder

composition

bound sialic acid, 0.5-1.5%

technique(s)

microbiological culture: suitable

solubility

NaOH: soluble 20 mg/mL

storage temp.

2-8°C

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General description

Mucins or mucus glycoproteins are the main macromolecular components of mammalian mucus. It was also used in a study to evaluate the sputum smears concentrated by cyto-centrifugation for detection of acid-fast bacilli.

Application

Mucin from porcine stomach was used in studies on the binding site of the galactose-specific agglutinin PA-IL from Pseudomonas aeruginosa.

Biochem/physiol Actions

Mucus forms the protective cover for all epithelial surfaces. The major structural component of mucus is gel-forming mucins. The mucus layer covering the intestinal epithelium has the MUC2 mucin as its central molecule. MUC2 is produced by goblet cells.

Preparation Note

Prepared according to the method of Glenister, et al., for use in complex growth media for dental plaque bacteria.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Kenny C Mok et al.
mBio, 11(6) (2020-12-10)
The beneficial human gut bacterium Akkermansia muciniphila provides metabolites to other members of the gut microbiota by breaking down host mucin, but most of its other metabolic functions have not been investigated. A. muciniphila strain MucT is known to use
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Human gut microbiota development has been associated with healthy growth but understanding the determinants of community assembly and composition is a formidable challenge. We cultured bacteria from serially collected fecal samples from a healthy infant; 34 sequenced strains containing 103,102
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Microbiome, 8(1), 33-33 (2020-03-13)
Human-targeted drugs may exert off-target effects or can be repurposed to modulate the gut microbiota. However, our understanding of such effects is limited due to a lack of rapid and scalable assay to comprehensively assess microbiome responses to drugs. Drugs
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Journal of clinical microbiology, 31(9), 2371-2374 (1993-09-01)
Early identification and isolation of tuberculosis patients is of utmost importance to minimize the risk of further epidemic spread of the disease. The traditional concentrated acid-fast smears are not very reliable tools for the presumptive diagnosis of tuberculosis. Acid-fast bacillus
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