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H0131

Sigma-Aldrich

DL-4-Hydroxy-3-methoxymandelic acid

≥98% (HPLC), powder

Sinónimos:

α,4-Dihydroxy-3-methoxybenzeneacetic acid, VMA, Vanillomandelic acid, Vanillylmandelic acid, Vanilmandelic acid

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About This Item

Fórmula lineal:
HOC6H3(OCH3)CH(OH)CO2H
Número de CAS:
55-10-7
Peso molecular:
198.17
Beilstein/REAXYS Number:
2213227
EC Number:
200-224-0
MDL number:
MFCD00004235
UNSPSC Code:
12352106
PubChem Substance ID:
24277743
NACRES:
NA.77

Quality Level

200

assay

≥98% (HPLC)

form

powder

color

white to off-white

mp

132-134 °C (dec.) (lit.)

solubility

H2O: ~50 mg/mL

storage temp.

2-8°C

SMILES string

OC1=C(OC)C=C(C(O)C(O)=O)C=C1

InChI

1S/C9H10O5/c1-14-7-4-5(2-3-6(7)10)8(11)9(12)13/h2-4,8,10-11H,1H3,(H,12,13)

InChI key

CGQCWMIAEPEHNQ-UHFFFAOYSA-N

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Biochem/physiol Actions

Epinephrine and norepineprine metabolite.

Features and Benefits

This compound is featured on the Dopamine and Norepinephrine Metabolism page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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W P Tormey et al.
Irish journal of medical science, 164(2), 146-150 (1995-04-01)
A study of the case notes from 101 of the 113 instances where at least one of the results was abnormal from the analysis of 24 hr urinary collections for noradrenaline, adrenaline, and dopamine and their metabolites 4-hydroxy-3-methoxy-mandelic acid (HMMA)
Sarah Garnier et al.
Journal of pediatric surgery, 47(8), e21-e23 (2012-08-21)
Mesoblastic nephroma is by far the most frequent intrarenal fetal tumor. To the best of our knowledge, we report the first case of a newborn with an intrarenal neuroblastoma that was discovered prenatally. An intrarenal echogenic and homogenous mass was
Wayne L Furman et al.
Investigational new drugs, 30(4), 1660-1670 (2011-07-29)
Gefitinib potently inhibits neuroblastoma proliferation in vitro, and the gefitinib/irinotecan combination shows greater than additive activity against neuroblastoma xenografts. This Phase II pilot study estimated the rate of response to two courses of intravenous irinotecan plus oral gefitinib in children
Prabal Deb et al.
Endocrine pathology, 23(3), 187-190 (2012-05-01)
Adrenal haemangioblastoma presenting clinically as pheochromocytoma is a rare manifestation of extraneural haemangioblastoma. We present an unusual case of von Hippel-Lindau (VHL) disease that had adrenal and cerebellar haemangioblastoma with multiple renal cysts, and a review of the literature. Unlike
Kai Li et al.
Journal of investigative surgery : the official journal of the Academy of Surgical Research, 25(2), 86-92 (2012-03-24)
This study assesses the clinical features of neuroblastoma and survival. Data for 98 patients between January 2000 and December 2006 at Children's Hospital of Fudan University, Shanghai, China, were retrospectively analyzed. Diagnostic methods included imaging, 24-hr urine catecholamines, bone marrow
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