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G6019

Sigma-Aldrich

Glyceraldehyde-3-phosphate Dehydrogenase from human erythrocytes

lyophilized powder, 50-150 units/mg protein

Sinónimos:

D-Glyceraldehyde 3-phosphate:NAD+ oxidoreductase (phosphorylating), GAPDH

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About This Item

Número de CAS:
9001-50-7
Comisión internacional de enzimas:
1.2.1.12 (BRENDA, IUBMB)
Número MDL:
MFCD00131203
Código UNSPSC:
12352204
NACRES:
NA.54

Formulario

lyophilized powder

Nivel de calidad

200

actividad específica

50-150 units/mg protein

composición

Protein, 40-70% biuret

Nº de acceso UniProt

P04406

actividad extraña

3-Phosphoglyceric phosphokinase ≤2%

temp. de almacenamiento

−20°C

Información sobre el gen

human ... GAPDH(2597)

Acciones bioquímicas o fisiológicas

Glyceraldehyde-3-phosphate dehydrogenase catalyzes the conversion of glyceraldehyde-3-phosphate to 1,3-bisphosphoglycerate as part of glycolysis. It has also been shown to have roles in initiation of apoptosis, transcription activation and the shuttling of ER to Golgi vesicles<<<18,New>>>.

Definición de unidad

One unit will reduce 1.0 μmole of 3-phosphoglycerate to D-glyceraldehyde 3-phosphate per min in a coupled system with 3-phosphoglyceric phosphokinase at pH 7.6 at 25 °C.

Forma física

Lyophilized powder containing sodium citrate buffer salts

Inhibidor

Referencia del producto
Descripción
Precios

I2512

Sodium iodoacetate, ≥98%

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

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Certificados de análisis (COA)

Lot/Batch Number
SLCG9330
SLCF0006
061M7024
019K7540
018K75551

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Bing Fang et al.
Biochimie, 95(2), 251-257 (2012-09-27)
siRNA is promising in anti-tumor therapy. The main challenge is lack of tumor-specific intracellular delivery. In this study, a 6 amino acids peptide (A1) with high affinity for vascular endothelial growth factor receptor-1 (VEGFR1) was conjugated with a cell penetrating
Pablo Moreno-Acosta et al.
Anticancer research, 32(10), 4319-4325 (2012-10-13)
The aim of this study was to evaluate the predictive utility of Insulin-like growth factor-1 receptor (IGF1R), IGF1, IGF2, Glyceraldehyde 3-phosphate dehydrogenase (GAPDH) and of hemoglobin levels for tumor response to exclusive radiotherapy, in patients with locally advanced Human papillomavirus
Milan Jirků et al.
The Journal of eukaryotic microbiology, 59(6), 537-547 (2012-08-01)
Several new species of trypanosomatids (Euglenozoa, Kinetoplastea, Trypanosomatidae), isolated from the intestines of Neotropical insects (Heteroptera), were genotyped on the basis of spliced leader RNA, and also defined phylogenetically using gene sequences of small subunit ribosomal RNA and glycosomal glyceraldehyde
Michele Salemi et al.
Tumori, 98(3), 86e-88e (2012-07-25)
Head and neck squamous cell carcinoma (HNSCC) is one of the most common cancers in the world. Risk factors for this cancer include tobacco and alcohol use, ultraviolet light exposure, and viral infection. Parkinson's disease is one of the most
Anne Gürtler et al.
Analytical biochemistry, 433(2), 105-111 (2012-10-23)
Western blots are used to specifically measure the relative quantities of proteins of interest in complex biological samples. Quantitative measurements can be subject to error due to process inconsistencies such as uneven protein transfer to the membrane. These non-sample-related variations
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