D3506

Sodium diethyldithiocarbamate trihydrate

• Sinónimos: Cupral, Diethyldithiocarbamic acid sodium salt
• Fórmula lineal: (C₂H₅)₂NCSSNa · 3H₂O
• Número de CAS: 20624-25-3
• Peso molecular: 225.31
• Beilstein/REAXYS Number: 3920507
• EC Number: 205-710-6
• MDL number: MFCD00150617
• UNSPSC Code: 12352200
• PubChem Substance ID: 57654092
• NACRES: NA.77

Propiedades

• vapor density: 5.9 (vs air)
• Quality Level: 200
• assay: ≥97% (perchloric acid titration)
• form: powder or crystals
• mp: 95-98.5 °C (lit.)
• solubility: water: 1 g/10 mL, slightly hazy
• storage temp.: room temp
• SMILES string: [H]O[H].[H]O[H].[H]O[H].CCN(CC)C(=S)S[Na]
• InChI: 1S/C5H11NS2.Na.3H2O/c1-3-6(4-2)5(7)8;;;;/h3-4H2,1-2H3,(H,7,8);;3*1H2/q;+1;;;/p-1
• InChI key: WWGXHTXOZKVJDN-UHFFFAOYSA-M

Descripción

Application

Spin trap used in conjunction with Fe²⁺ to detect NO in brain, kidney, liver, and other tissues. Simultaneous direct measurement of NO* and pO₂ has been reported. A copper chelator, it has been used to quantitate copper in biological materials by ESR and is an inhibitor of superoxide dismutase, ascorbate oxidase, and other enzymes.

Biochem/physiol Actions

Inhibits induction of macrophage nitric oxide synthase.

Features and Benefits

This compound is a featured product for ADME Tox research. Click here to discover more featured ADME Tox products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound is featured on the Dopamine, Norepinephrine and Epinephrine Synthesis page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Caution

May form insoluble oxidation products in storage. Sensitivity in colorimetric copper determination not usually affected.

Información de seguridad

• pictograms: GHS05,GHS07
• signalword: Danger
• hcodes: H302,H315,H318
• pcodes: P264 - P270 - P280 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Eye Dam. 1 - Skin Irrit. 2
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves