Creatine Kinase is a dimer that exists as three isozymes: MM (muscle), MB (hybrid) and BB (brain).
C9858
Creatine Kinase MM Fraction from human heart
lyophilized powder
Sinónimos:
CK-MM Fraction, Human CK MM, Human Creatine Kinase
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Specificity
One unit will transfer 1.0 μmole of phosphate from creatine phosphate to ADP per minute at 37 °C (measured at 340 nm as one equimolar amount of NADH produced by coupled reaction).
Application
Creatine kinase MM fraction from human heart has been used in a study to investigate the importance of intraoperative and postoperative cardiac medical therapy in emergency coronary artery bypass grafting for acute myocardial infarction. Creatine kinase MM fraction from human heart has also been used in a study to investigate the circadian dependence of infarct size and left ventricular function after ST slevation myocardial infarction.
Biochem/physiol Actions
May be used as a control or calibrator in monitoring myocardial injury.
Warning
All human source materials have tested negative for HIV1, HIV2, HCV antibodies and HbsAg. No test guarantees a product to be non-infectious. Therefore, all material derived from human fluids or tissues should be considered as potentially infectious.
Unit Definition
One unit will transfer one micromole of phosphate from creatine phosphate to ADP per minute at 37 deg C.
Physical form
Lyophilized powder containing Tris-HCl, EDTA and N-acetyl cysteine.
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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Akira Sezai et al.
Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia, 18(4), 338-346 (2012-05-11)
The results of emergency coronary artery bypass grafting (CABG) for acute myocardial infarction (AMI) are less than satisfactory, and readmission for cardiac events is common. 105 patients underwent emergency CABG for AMI. We examined the long-term results of emergency CABG
Akira Sato et al.
Journal of the American College of Cardiology, 59(8), 730-738 (2012-02-22)
This study evaluated the clinical value of myocardial contrast delayed enhancement (DE) with multidetector computed tomography (MDCT) for predicting clinical outcome after acute myocardial infarction (AMI). Although some studies have described the use of MDCT for assessment of myocardial viability
Ronald Reiter et al.
Circulation research, 110(1), 105-110 (2011-11-19)
In rodents, infarct size after ischemia/reperfusion exhibits a circadian dependence on the time of coronary occlusion. It is not known if a similar circadian dependence of infarct size occurs in humans. To determine if humans exhibit a circadian dependence of
Helen Lee et al.
The European journal of neuroscience, 31(8), 1388-1401 (2010-04-14)
Horizontal cells are lateral interneurons that participate in visual processing in the outer retina but the cellular mechanisms underlying transmitter release from these cells are not fully understood. In non-mammalian horizontal cells, GABA release has been shown to occur by
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