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89517

Sigma-Aldrich

(S)-3,4-Dihydroxybutyric acid lithium salt hydrate

≥95.0% (GC)

Sinónimos:

(S)-3,4-Dihydroxybutanoic acid lithium salt hydrate

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About This Item

Fórmula empírica (notación de Hill):
C4H8O4 · xLi+ · yH2O
Número de CAS:
51267-44-8
Peso molecular:
120.10 (free acid basis)
UNSPSC Code:
12352106
PubChem Substance ID:
329769745
NACRES:
NA.25

Quality Level

100

assay

≥85% (free acid, qNMR)
≥95.0% (GC)

form

solid

optical activity

[α]/D -25±5°, 24 hr, c = 0.1 in 0.1 M HCl

storage temp.

−20°C

SMILES string

O[C@H](CO)CC(O)=O

InChI

1S/C4H8O4/c5-2-3(6)1-4(7)8/h3,5-6H,1-2H2,(H,7,8)/t3-/m0/s1

InChI key

DZAIOXUZHHTJKN-VKHMYHEASA-N

Biochem/physiol Actions

3,4-Dihydroxybutyric acid is a normal human urinary metabolite that is excreted in increased concentration in patients with succinic semialdehyde dehydro- genase (SSADH) deficiency, while healthy adults excrete 0.37 +/- 0.15 (SD) mmoles of 3,4- dihydroxybutyrate per 24 hr. The renal clearance of this compound is roughly equal that of creatinine. This metabolite is also detectable in blood.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

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Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 776(1), 57-63 (2002-07-20)
We describe the rapid and sensitive detection of 4-hydroxybutyric acid, which is a marker compound for succinic semialdehyde dehydrogenase (SSADH) deficiency. Urinary 4-hydroxybutyric acid and 3,4-dihydroxybutyric acid were targeted, quantified by gas chromatography-mass spectrometry after simplified urease digestion in which
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