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46943

Sigma-Aldrich

Fluorescein dilaurate

suitable for fluorescence, ≥97.0% (HPCE)

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About This Item

Fórmula empírica (notación de Hill):
C44H56O7
Número de CAS:
7308-90-9
Peso molecular:
696.91
Beilstein/REAXYS Number:
6034843
EC Number:
230-764-2
MDL number:
MFCD00038409
UNSPSC Code:
12352106
PubChem Substance ID:
57650888
NACRES:
NA.32

Quality Level

100

assay

≥97.0% (HPCE)

form

powder

solubility

ethanol: soluble

fluorescence

λex 490 nm; λem 514 nm in 0.1 M Tris pH 8.0 (esterase)

suitability

suitable for fluorescence

SMILES string

CCCCCCCCCCCC(=O)Oc1ccc2c(Oc3cc(OC(=O)CCCCCCCCCCC)ccc3C24OC(=O)c5ccccc45)c1

InChI

1S/C44H56O7/c1-3-5-7-9-11-13-15-17-19-25-41(45)48-33-27-29-37-39(31-33)50-40-32-34(49-42(46)26-20-18-16-14-12-10-8-6-4-2)28-30-38(40)44(37)36-24-22-21-23-35(36)43(47)51-44/h21-24,27-32H,3-20,25-26H2,1-2H3

InChI key

MYTRGBGGRICZGN-UHFFFAOYSA-N

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Application

Fluorescein dilaurate is suitable as fluorogenic substrate for esterases/lipases and used in the pancreolauryl test for chronic pancreatitis.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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F Seibold et al.
Journal of clinical gastroenterology, 22(3), 202-206 (1996-04-01)
Pancreatic autoantibodies (PABs) are found in 31% of patients with Crohn's disease (CD), but they do not correlate with the activity of intestinal disease or the incidence of acute pancreatitis. Exocrine pancreatic insufficiency has been observed in patients with CD.
E Małecka-Panas et al.
Polskie Archiwum Medycyny Wewnetrznej, 94(4), 315-323 (1995-10-01)
The aim of the presented study was a comparative evaluation of the three indirect pancreatic function tests: pancreolauryl-test (PLT), NBT-PABA test and faecal chymotrypsin (CH) efficacy in detecting pancreatic exocrine function impairment in advanced chronic pancreatitis (acp). 30 patients with
J Sarles
Annales de pediatrie, 39(4), 221-225 (1992-04-01)
The exocrine pancreas produces many of the enzymes responsible for the digestion of food. Severe alterations in exocrine pancreas function cause malabsorption which predominantly affects fats. Unfortunately, because it is a deep organ the pancreas is a difficult target for
Maria Beatriz Di Carlo et al.
Acta gastroenterologica Latinoamericana, 40(2), 128-133 (2010-07-22)
The pancreas is a mixed gland that takes part in the digestion of nutrients and in the homeostasis ofglycemia. Chronic pancreopathy is the cause of secretory insufficiency, characterized by an inflammatory process that leads to fibrosis of the pancreas, with
A L Trewick
Annals of clinical biochemistry, 35 ( Pt 2), 274-278 (1998-04-21)
The influence of the glucose concentration in urines being assayed as part of a pancreolauryl test was investigated. Paired patient urines (n = 5) were assayed at 60 degrees and 70 degrees C, before and after spiking to 5% glucose.
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