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239658

Supelco

Bisphenol A

≥99%

Sinónimos:

2,2-Bis(4-hydroxyphenyl)propane, 4,4′-Isopropylidenediphenol

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About This Item

Fórmula lineal:
(CH3)2C(C6H4OH)2
Número de CAS:
80-05-7
Peso molecular:
228.29
Beilstein/REAXYS Number:
1107700
EC Number:
201-245-8
MDL number:
MFCD00002366
UNSPSC Code:
12000000
PubChem Substance ID:
24854386
NACRES:
NA.21

Quality Level

100

assay

≥99%

form

solid

bp

220 °C/4 mmHg (lit.)

mp

158-159 °C (lit.)

SMILES string

CC(C)(c1ccc(O)cc1)c2ccc(O)cc2

InChI

1S/C15H16O2/c1-15(2,11-3-7-13(16)8-4-11)12-5-9-14(17)10-6-12/h3-10,16-17H,1-2H3

InChI key

IISBACLAFKSPIT-UHFFFAOYSA-N

Gene Information

mouse ... Esr1(13982)
rat ... Ar(24208)

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General description

Bisphenol A (BPA) is a diphenylmethane derivative, commonly used in the production of polycarbonate plastics, epoxy resins, and various other plastic-based consumer products. It is also known to exhibit strong endocrine-disrupting ability.

Application

The analytical standard can also be used as follows:
  • Quantitative analysis of bisphenol A and bisphenol S in three plastic product samples of a mineral water bottle, polycarbonate bottle, and baby bottle, using a modified glassy carbon electrode (GCE) sensor based on a crystalline covalent organic framework (COF)
  • Simultaneous determination of bisphenol A, S, and F in 112 samples of thermal paper receipts by liquid chromatography coupled to mass spectrometry (LC-MS) following their ultrasound-assisted extraction
  • Development and validation of a gas chromatography-tandem mass spectrometry (GC-MS/MS) method for the measurement of bisphenol A and 18 BPA-related compounds in 30 breast milk samples after their solid phase extraction (SPE)
  • Construction of an electrochemical sensor based on multi-walled carbon nanotubes (MWCNTs) modified glassy carbon electrode (GCE) for the determination of bisphenol A & S in river water and thermal paper samples by cyclic voltammetry (CV)
  • Determination of bisphenol A in urine samples using a novel method based on miniaturized QuEChERS extraction and gas chromatography-mass spectrometry (GC-MS)
  • Investigate the bisphenol A content from glass or Pasteur pipettes in biological liquids from maternal women using high-performance liquid chromatography (HPLC).

signalword

Danger

Hazard Classifications

Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Repr. 1B - Skin Sens. 1 - STOT SE 3

target_organs

Respiratory system

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk_germany

WGK 3

flash_point_f

440.6 °F - closed cup

flash_point_c

227 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

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Certificados de análisis (COA)

Lot/Batch Number
MKCQ9051
MKCM7053
MKCG8489
MKCD7508
MKCC7654

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Sanjay Basak et al.
Reproductive toxicology (Elmsford, N.Y.), 82, 72-79 (2018-10-24)
Humans are exposed to Bisphenol A (BPA) from the consumer products and plastic substances. However, impacts of low levels of BPA exposure on placental developmental processes such as first trimester trophoblast cell growth, angiogenesis and epigenetic modifications are not well
Maternal bisphenol-A levels at delivery: a looming problem?
Padmanabhan V, et al.
Journal of Perinatology : Official Journal of the California Perinatal Association, 28, 258-258 (2008)
Damaskini Valvi et al.
Epidemiology (Cambridge, Mass.), 24(6), 791-799 (2013-09-17)
Increasing experimental evidence suggests that prenatal bisphenol A (BPA) exposure induces offspring weight gain, but these effects remain largely unexplored in humans. We examined the effects of prenatal BPA exposure on postnatal growth and obesity. BPA concentrations were measured in
Marie Tohmé et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 28(7), 3124-3133 (2014-04-20)
Bisphenol A (BPA) is an endocrine disruptor that displays estrogenic activity. Several reports suggest that BPA may have estrogen receptor-independent effects. In zebrafish, 50 μM BPA exposure induces otic vesicle abnormalities, including otolith aggregation. The purpose of this study was
Tinne Geens et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 50(10), 3725-3740 (2012-08-15)
Due to the large number of applications of bisphenol-A (BPA), the human exposure routes are multiple. We aimed to review shortly the food and non-food sources of BPA, and to evaluate their contribution to the human exposure. Food sources discussed
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Protocolos

Determination of Bisphenol A in Drinking Water

A comprehensive sample preparation and analytical procedure was developed by Supelco for determining BPA in drinking water.

Determinación del bisfenol A en el agua potable

Supelco desarrolló un procedimiento integral analítico y de preparación de muestras para determinar el BPA en el agua potable.

Determinación del bisfenol A en el agua potable

Supelco desarrolló un procedimiento integral analítico y de preparación de muestras para determinar el BPA en el agua potable.

Determinación del bisfenol A en el agua potable

Supelco desarrolló un procedimiento integral analítico y de preparación de muestras para determinar el BPA en el agua potable.

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