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17797

Sigma-Aldrich

Physcion

≥98.0% (TLC)

Sinónimos:

1,8-Dihydroxy-3-methoxy-6-methylanthraquinone, 6-O-Methylemodin, 6-Methoxychrysophanic acid, Emodin-3-methyl ether, Parietin, Rheochrysidin

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About This Item

Fórmula empírica (notación de Hill):
C16H12O5
Número de CAS:
521-61-9
Peso molecular:
284.26
Beilstein/REAXYS Number:
6770499
EC Number:
208-315-7
MDL number:
MFCD00017374
UNSPSC Code:
85151701
PubChem Substance ID:
57647675
NACRES:
NA.25

Quality Level

100

assay

≥98.0% (TLC)

antibiotic activity spectrum

fungi

SMILES string

COc1cc(O)c2C(=O)c3c(O)cc(C)cc3C(=O)c2c1

InChI

1S/C16H12O5/c1-7-3-9-13(11(17)4-7)16(20)14-10(15(9)19)5-8(21-2)6-12(14)18/h3-6,17-18H,1-2H3

InChI key

FFWOKTFYGVYKIR-UHFFFAOYSA-N

Gene Information

human ... ELA2(1991)

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Application

Physcion can be used to study antibiotics, antifungals, bioactive small molecules and cell biology. Physcion has been used in a study to test the cytotoxicity of juglanthraquinone C on human cancer cells. Physcion has also been used in a study that investigated the metabolic regulatory effects of Rheum undulatum in a high-fat diet model.

Biochem/physiol Actions

Anthraquinone-derivative found in medicinal herbs.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H302

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Aloe-emodine phyproof® Reference Substance

PHL89157

Aloe-emodine

Aloe-emodine analytical standard

Supelco

93938

Aloe-emodine

Chrysophanol phyproof® Reference Substance

PHL89378

Chrysophanol

2,3,5,4′-Tetrahydroxystilbene 2-O-β-D-glucoside ≥98% (HPLC)

Sigma-Aldrich

SML0834

2,3,5,4′-Tetrahydroxystilbene 2-O-β-D-glucoside

Rhein technical grade

Sigma-Aldrich

275611

Rhein

Rhein phyproof® Reference Substance

PHL89385

Rhein

Polydatin ≥95% (HPLC)

Sigma-Aldrich

15721

Polydatin

Yao Yao et al.
Apoptosis : an international journal on programmed cell death, 17(8), 832-841 (2012-04-10)
Juglanthraquinone C (1,5-dihydroxy-9,10-anthraquinone-3-carboxylic acid, JC), a naturally occurring anthraquinone isolated from the stem bark of Juglans mandshurica, shows strong cytotoxicity in various human cancer cells in vitro. Here, we first performed a structure-activity relationship study of six anthraquinone compounds (JC
Phil-Dong Moon et al.
Molecules (Basel, Switzerland), 24(8) (2019-04-18)
Physcion is well known for the treatment of carcinoma. However, the therapeutic effect of physcion on atopic dermatitis (AD) through the inhibition of thymic stromal lymphopoietin (TSLP) level remains largely unknown. In this study, we investigated the anti-AD effect of
Simeon F Kouam et al.
Journal of natural products, 69(2), 229-233 (2006-02-28)
One new prenylated 1,4-anthraquinone and three new prenylated anthranols, named kengaquinone (1) and kenganthranols A (2), B (3), and C (4), were isolated from a hexane extract of the stem bark of Harungana madagascariensis. Six known compounds including anthraquinones, anthrones
Ming-Yi Shen et al.
PloS one, 6(11), e27480-e27480 (2011-11-17)
Plants provide a rich source of lead compounds for a variety of diseases. A novel approach combining phytochemistry and chemotaxis assays was developed and used to identify and study the mechanisms of action of the active compounds in F. japonica
Santosh Pandit et al.
Biofouling, 28(3), 279-287 (2012-03-23)
Polygonum cuspidatum is a plant with spreading rhizomes and numerous reddish-brown stems that has been used in Korean folk medicine to improve oral hygiene. Nevertheless, there are no reports related to its possible effect on the virulence of dental biofilms.
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