77253

Heptafluorobutyric anhydride

for GC derivatization, LiChropur^™, ≥99.0%

• Sinónimos: HFAA, HFBA, Perfluorobutyric anhydride
• Fórmula lineal: (CF₃CF₂CF₂CO)₂O
• Número de CAS: 336-59-4
• Peso molecular: 410.06
• Beilstein: 856036
• Número CE: 206-410-8
• Número MDL: MFCD00000432
• Código UNSPSC: 12000000
• ID de la sustancia en PubChem: 329767572
• NACRES: NA.22

Propiedades

• grado: for GC derivatization
• Nivel de calidad: 100
• Ensayo: ≥99.0% (GC); ≥99.0%
• Formulario: liquid
• calidad: LiChropur^™
• idoneidad de la reacción: reagent type: derivatization reagent; reaction type: Acylations
• técnicas: gas chromatography (GC): suitable
• índice de refracción: n20/D 1.287 (lit.)
• bp: 108-110 °C (lit.)
• mp: −43 °C (lit.)
• densidad: 1.674 g/mL at 20 °C (lit.); 1.674 g/mL at 20 °C
• cadena SMILES: FC(F)(F)C(F)(F)C(F)(F)C(=O)OC(=O)C(F)(F)C(F)(F)C(F)(F)F
• InChI: 1S/C8F14O3/c9-3(10,5(13,14)7(17,18)19)1(23)25-2(24)4(11,12)6(15,16)8(20,21)22
• Clave InChI: UFFSXJKVKBQEHC-UHFFFAOYSA-N

Descripción

Descripción general

Heptafluorobutyric anhydride is a perfluoroacylated acylation reagent, that forms stable, volatile derivatives with alcohols, amines, and phenols. It is majorly used to prepare electron-capturing derivatives for GC/electron capture detection. It is generally used with an acid scavenger, to help drive the reaction to completion and to prevent column damage from acidic by-products of the derivatization reaction. It is also used for the frequent testing of drugs of abuse such as, amphetamines and phencyclidine by GC-MS technique.

Aplicación

Learn more in the Product Information

Envase

Clear borosilicate glass, high hydrolytic resistance (Type I)

Nota de análisis

Suitable for derivatization of aldosterone, digoxin, digitoxin and metabolites, estradiol, postaglandins F_1α and F_2α, 3-oxo-Δ⁴-steroids, steroids and testosterone.

Otras notas

HFAA acylates amines, amino acids and other compounds. HFBA derivatives are highly volatile: used in GC separation

Reagent for 3-enol heptafluorobutyrate, heptafluorobutyrate, heptafluorobutyryl, 17-heptafluorobutyryl and 17-heptafluorobutyrate.

Información legal

LiChropur is a trademark of Merck KGaA, Darmstadt, Germany

Información de seguridad

• Pictogramas: GHS05
• Palabra de señalización: Danger
• Frases de peligro: H314
• Consejos de prudencia: P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 - P363 - P405
• Clasificaciones de peligro: Skin Corr. 1B
• Código de clase de almacenamiento: 8A - Combustible corrosive hazardous materials
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable
• Equipo de protección personal: Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter