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Merck

00140585

Isoquercitrin

primary reference standard

Sinónimos:

Quercetin 3-β-D-glucoside, 3,3′,4′,5,7-Pentahydroxyflavone 3-β-glucoside, Isoquercitrin

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About This Item

Fórmula empírica (notación de Hill):
C21H20O12
Número de CAS:
Peso molecular:
464.38
Beilstein:
100989
Número MDL:
Código UNSPSC:
85151701
ID de la sustancia en PubChem:
NACRES:
NA.24

grado

primary reference standard

caducidad

limited shelf life, expiry date on the label

fabricante / nombre comercial

HWI

técnicas

HPLC: suitable
gas chromatography (GC): suitable

cadena SMILES

OC[C@H]1O[C@@H](OC2=C(Oc3cc(O)cc(O)c3C2=O)c4ccc(O)c(O)c4)[C@H](O)[C@@H](O)[C@@H]1O

InChI

1S/C21H20O12/c22-6-13-15(27)17(29)18(30)21(32-13)33-20-16(28)14-11(26)4-8(23)5-12(14)31-19(20)7-1-2-9(24)10(25)3-7/h1-5,13,15,17-18,21-27,29-30H,6H2/t13-,15-,17+,18-,21+/m1/s1

Clave InChI

OVSQVDMCBVZWGM-QSOFNFLRSA-N

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Descripción general

Isoquercitrin is a flavonoid, glucoside derivative of quercitrin, and protein disulfide isomerase (PDI) inhibitor. Obtained from the leaf of medicinal plants, such as Apocynum venetum among others, it is known for its anti-oxidant and anti-thrombotic activities.
Produced and qualified by HWI pharma services GmbH.
Exact content measured by quantitative NMR can be found on the certificate.

Aplicación

The primary reference standard can be used for identification, assay, and purity testing, method development, and validation.It can also be used as follows:
  • Development of a synergistic cloud point extraction (SCPE) method for the extraction of isoquercitrin in rat plasma samples and its subsequent analysis by high-performance liquid chromatography (HPLC)
  • Electrochemical analysis of isoquercitrin and epigallocatechin gallate by cyclic voltammetry using carbon nanotubes based electrode
  • Simultaneous determination of rutin and isoquercitrin by differential pulse voltammetry (DPV) using glassy carbon electrode (GCE) modified with deposition of thio-β-cyclodextrin functionalized graphene/palladium nanoparticles (SH-β-CD-Gr/PdNPs) for pharmaceutical and medical analysis
  • Multi-residue analysis of isoquercitrin, campesterol, emodin 8-O-β-D-glucopyranoside, and quercetin in dried stem and flower extracts of Reynoutria sachalinensis by high-performance liquid chromatography coupled with diode-array detection

Otras notas

This compound is commonly found in plants of the genus: arnica sambucus

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 3


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Certificados de análisis (COA)

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Visite la Librería de documentos

Anti-inflammatory activity of quercetin and isoquercitrin in experimental murine allergic asthma.
Rogerio AP
Inflammation Research, 56(10), 402-408 (2007)
New insight into the flavonoid composition of Chenopodium botrys.
Bojilov, D., S. Dagnon, and I. Ivanov.
Phytochemistry Letters (2017)
Qi Chang et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 59(3), 549-555 (2005-03-12)
The present study was to investigate oral absorption of the two similar flavonoid glycosides, isoquercitrin (IQ, quercetin-3-O-glucoside) and hyperoside (HP, quercetin-3-O-galactoside) in rats. Two groups of male SD rats received an oral dose of either IQ (4.5 mg/kg) or HP
Difference in absorption of the two structurally similar flavonoid glycosides, hyperoside and isoquercitrin, in rats.
Chang Q
European Journal of Pharmaceutics and Biopharmaceutics, 59(3), 549-555 (2005)
Effect of acyl donor chain length on isoquercitrin acylation and biological activities of corresponding esters.
Salem, Jamila Hadj, et al.
Process. Biochem., 45.3, 382-389 (2010)

Protocolos

HPLC Analysis of Polyphenols in Nero d'Avola Red Wine on Discovery® HS C18 (UV 280 nm)

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