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Merck
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Key Documents

8.51014

Sigma-Aldrich

Fmoc-OSu

≥99.0% (HPLC), for peptide synthesis, Novabiochem®

Sinónimos:

Fmoc-OSu, FMOC-ONSu, N-(9H-Fluoren-9-ylmethoxycarbonyloxy)succinimide, N-(9-Fluorenylmethoxycarbonyloxy)succinimide, 9-Fluorenylmethyl-succinimidyl carbonate

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About This Item

Fórmula empírica (notación de Hill):
C19H15NO5
Número de CAS:
82911-69-1
Peso molecular:
337.33
MDL number:
MFCD00010733
UNSPSC Code:
12352108
EC Index Number:
433-520-5
NACRES:
NA.22

product name

Fmoc-OSu, Novabiochem®

Quality Level

200

product line

Novabiochem®

assay

≥99.0% (HPLC)

form

powder

manufacturer/tradename

Novabiochem®

mp

145-148 °C

application(s)

peptide synthesis

functional group

Fmoc

storage temp.

2-8°C

InChI

1S/C19H15NO5/c21-17-9-10-18(22)20(17)25-19(23)24-11-16-14-7-3-1-5-12(14)13-6-2-4-8-15(13)16/h1-8,16H,9-11H2

Inchi Key

WMSUFWLPZLCIHP-UHFFFAOYSA-N

Categorías relacionadas

General description

Reagent for the preparation of pure Fmoc-amino acids that are free from contamination by Fmoc-dipeptides [1,2,3].

Literature references

[1] A. Paquet (1982) Can. J. Chem., 60, 976.
[2] L. Lapatsanis, et al. (1983) Synthesis, 671.
[3] G. F. Sigler, et al. (1983) Biopolymers, 22, 2157.

Application

  • Sequence-defined positioning of amine and amide residues to control catechol driven wet adhesion: This study uses Fmoc-OSu for selective functionalization of amines, demonstrating its role in synthesizing complex molecules with specific adhesive properties (Fischer et al., 2020).
  • Fmoc-OASUD: A new reagent for the preparation of Fmoc-amino acids free from impurities resulting from Lossen rearrangement: Discusses the development of Fmoc-OASUD as a superior alternative to Fmoc-OSu, reducing impurities in peptide synthesis processes (Rao et al., 2016).

Linkage

Replaces: 01-63-0001

Analysis Note

Colour (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Assay (HPLC, area%): ≥ 99.0 % (a/a)
Solubility (1 mmole in 2 ml DMF): clearly soluble

Legal Information

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

Exclamation markEnvironment
GHS07,GHS09

signalword

Warning

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Chronic 2 - Skin Sens. 1

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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