8.14371

Triethylamine trishydrofluoride

for synthesis

• Sinónimos: Triethylamine trishydrofluoride
• Fórmula lineal: (C₂H₅)₃N · 3 HF
• Número de CAS: 73602-61-6
• Peso molecular: 161.21
• MDL number: MFCD00043294
• UNSPSC Code: 12352107
• EC Index Number: 277-550-5
• NACRES: NA.22

Propiedades

• Quality Level: 200
• form: liquid
• pH: 3 (20 °C in H₂O, saturated aqueous solution)
• bp: 70 °C/19.9 hPa
• transition temp: flash point 88 °C
• density: 1.00 g/cm³ at 20 °C
• storage temp.: 2-30°C
• InChI: 1S/C6H15N.3FH/c1-4-7(5-2)6-3;;;/h4-6H2,1-3H3;3*1H
• Inchi Key: IKGLACJFEHSFNN-UHFFFAOYSA-N

Descripción

Application

• Asymmetric synthesis of fluoroamines from chiral aziridines: This study explores the use of triethylamine trishydrofluoride in the synthesis of fluoroamines, highlighting its role in enhancing reaction selectivity and efficiency (Park et al., 2014).
• Recent advance in the synthesis of (1, 1-difluoroethyl) arenes: This paper discusses recent advancements in the synthesis of difluoroethyl arenes using triethylamine trishydrofluoride, contributing to the development of new fluorination techniques (Li et al., 2018).
• Quantification of hydrogen fluoride-based reagents using a bifunctional NMR internal standard: Describes the quantification of reagents like triethylamine trishydrofluoride in chemical syntheses, emphasizing the accuracy of measurement techniques (Hammond et al., 2016).
• Extensive CRISPR RNA modification reveals chemical compatibility and structure-activity relationships for Cas9 biochemical activity: This research utilizes triethylamine trishydrofluoride for RNA modifications in CRISPR-Cas9 processes, showing its potential in genetic engineering (O′Reilly et al., 2019).

Analysis Note

Assay (HClO₄): ≥ 98.0 %
Colour (visual): colourless, almost colourless
Density (d 20 °C/ 4 °C): 0.995 - 1.000
Identity (IR): passes test

Información de seguridad

• pictograms: GHS05,GHS06
• signalword: Danger
• hcodes: H300 + H310 + H330 - H314
• pcodes: P260 - P271 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 1 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Eye Dam. 1 - Skin Corr. 1A
• Storage Class: 6.1A - Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials
• wgk_germany: WGK 3
• flash_point_f: 190.4 °F
• flash_point_c: 88 °C