126654
Albumin, Human Serum, Non-denatured
Sinónimos:
Albumin, Human Serum, Non-denatured
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About This Item
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descripción
Merck USA index - 14, 8468
Ensayo
≥95% (SDS-PAGE)
Formulario
lyophilized solid (Salt-free)
fabricante / nombre comercial
Calbiochem®
condiciones de almacenamiento
OK to freeze
técnicas
protein quantification: suitable
pI
4.7
solubilidad
water: 20 mg/mL
Condiciones de envío
ambient
temp. de almacenamiento
2-8°C
cadena SMILES
FC(F)(F)C(F)(F)C(F)(F)F
InChI
1S/C3F8/c4-1(5,2(6,7)8)3(9,10)11
Clave InChI
QYSGYZVSCZSLHT-UHFFFAOYSA-N
Categorías relacionadas
Descripción general
High purity plasma protein prepared under non-denaturing conditions.
Human serum albumin (HSA) is the most abundant protein present in the plasma. It is a monomeric multi-domain macromolecule comprising three homologous domains, numbered I, II, and III. Each domain consists of subdomains A and B with common structural motifs. The HSA gene is mapped to the human chromosome 4q13.3.
Aplicación
Albumin, human serum, non-denatured has been used:
- to determine the contribution of albumin protein complexes to esterase activity in saliva,
- in tris buffer for monomer degradation studies and in protein adhesion assay
- to study the effect of Cu2+ and Zn2+ ions on human serum albumin interaction with plasma unsaturated fatty acids
Acciones bioquímicas o fisiológicas
Human serum albumin (HSA) functions as a carrier for fatty acids, steroids, and thyroid hormones. It is used as a supplement in cell culture medium to produce vaccines and pharmaceuticals. HSA is a potential biomarker for various diseases, like cancer, rheumatoid arthritis, ischemia, and post-menopausal obesity. It is also used to treat surgical blood loss, trauma, hemorrhage, and cardiopulmonary bypass. HSA is implicated in biological applications such as implantable biomaterials, surgical adhesives and sealants, and bio chromatography.
Advertencia
Toxicity: Standard Handling (A)
Nota de preparación
Prepared from serum that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
Reconstitución
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
Otras notas
Travis, J., and Pannell, R. 1973. Clin. Chem. Acta49, 49.
Información legal
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Cláusula de descargo de responsabilidad
RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.
Código de clase de almacenamiento
11 - Combustible Solids
Clase de riesgo para el agua (WGK)
WGK 3
Punto de inflamabilidad (°F)
Not applicable
Punto de inflamabilidad (°C)
Not applicable
Certificados de análisis (COA)
Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»
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