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C-106

Supelco

Cortisol solution

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

Sinónimos:

Hydrocortisone solution, 17-Hydroxycorticosterone, Cortisol

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About This Item

Número de CAS:
50-23-7
Número CE:
200-659-6
Número MDL:
MFCD00011654
Código UNSPSC:
41116107
ID de la sustancia en PubChem:
329774841
NACRES:
NA.24
En este momento no podemos mostrarle ni los precios ni la disponibilidad

grado

certified reference material

Nivel de calidad

300

Formulario

liquid

Características

Snap-N-Spike®/Snap-N-Shoot®

envase

ampule of 1 mL

fabricante / nombre comercial

Cerilliant®

concentración

1.0 mg/mL in methanol

técnicas

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

aplicaciones

clinical testing
clinical testing

Formato

single component solution

temp. de almacenamiento

−20°C

cadena SMILES

C[C@]12CCC(=O)C=C1CC[C@H]3[C@@H]4CC[C@](O)(C(=O)CO)[C@@]4(C)C[C@H](O)[C@H]23

InChI

1S/C21H30O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h9,14-16,18,22,24,26H,3-8,10-11H2,1-2H3/t14-,15-,16-,18+,19-,20-,21-/m0/s1

Clave InChI

JYGXADMDTFJGBT-VWUMJDOOSA-N

Información sobre el gen

human ... NR3C1(2908)

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Descripción general

Cortisol or hydrocortisone, also known as the stress hormone, is aglucocorticoid steroid. It is released by the adrenal glands and is involved inmaintaining the circadian rhythm. The hormone is measured in whole blood by LC-MS/MS for newborn screening of congenital adrenal hyperplasia (CAH) and in serum or plasma by LC-MS/MS for determination of several diseases including Cushing’s syndrome, Addison’s disease, and Sheehan’s syndrome.

Aplicación

This Certified Reference Material (CRM) in solution can also be used as follows:
  • Development of a disposable immunosensor based on direct competitive-enzyme linked immunoassay (DC-ELISA) to determine cortisol in human saliva samples
  • Quantitative analysis of cortisol in human hair samples by a liquid-chromatography-tandem mass spectrometric (LC-MS/MS) method
  • Selective and sensitive analysis of both cortisol and cortisone in human hair samples by an automated solid phase extraction (SPE) method combined with liquid chromatography (LC) coupled to electrospray ionization-tandem mass spectrometry (ESI-MS3)
  • Multi-residue determination of cortisol, cortisone, and their three tetrahydro metabolites from human urine samples by an LC-MS/MS method
  • Human saliva analysis for the estimation of cortisol and cortisone by ionic liquid dispersive liquid-liquid microextraction (IL-DLLME) and liquid chromatography combined with ultra-violet/visible (UV/Vis) detection

Características y beneficios

  • Fully characterized under ISO/IEC 17025 and ISO 17034 accreditation
  • Accompanied with a comprehensive Certificate of Analysis (CoA) with data on stability, homogeneity, accuracy of concentration, uncertainty, and traceability
  • Rigorously tested through real-time stability studies to ensure accuracy and shelf life
  • Gravimetrically prepared using qualified precision balances to ensure minimal uncertainty
  • Flame sealed under argon into ampoules for long-term shelf life
  • Offered in a convenient, DEA-exempt format to improve laboratory efficiency

Información legal

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

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Palabra de señalización

Danger

Clasificaciones de peligro

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

Órganos de actuación

Eyes,Central nervous system

Código de clase de almacenamiento

3 - Flammable liquids

Clase de riesgo para el agua (WGK)

WGK 2

Punto de inflamabilidad (°F)

49.5 °F - closed cup

Punto de inflamabilidad (°C)

9.7 °C - closed cup

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Certificados de análisis (COA)

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Visite la Librería de documentos

Sanda Tesanović et al.
Collegium antropologicum, 37(2), 367-371 (2013-08-15)
We conducted this study to determine the degree of obesity influence on the hypoglycemic response of growth hormone and cortisol after weight loss of 5%. A total of 45 non-diabetic, male subjects followed in the outpatient endocrinological departments were divided
M V Bezruchko et al.
Klinichna khirurhiia, (3)(3), 22-25 (2013-05-31)
The results of comparison between the operation stress degree in various kinds of surgical interventions, performed for an acute cholecystitis, using determination of cortizol, prolactin and glucose content before the operation, intraoperatively and postoperatively in 50 patients, are adduced. There
Maria Szcześniak et al.
Polimery w medycynie, 43(1), 29-34 (2013-07-03)
AIM OF THE STUDY. The study on the effect of absorption promotors on the properties of hydrogels prepared from Carbopol 934P basis containing 1% hydrocortisone. hydrocortysone, Carbopol 934P, propylene glycol-1,2 N,N-dimethylacetamide purified water to P Ph 9th Ed., ethanol 760
I A Odeniyi et al.
Nigerian journal of clinical practice, 16(3), 269-272 (2013-06-19)
Cushing's syndrome results from chronic exposure to excessive circulating levels of glucocorticoids. To confirm the clinical suspicion, biochemical tests are needed. These biochemical tests include the measurement of excess total endogenous cortisol secretion assessed by 24-hour urinary free cortisol (UFC)
Wanpen Turakitwanakan et al.
Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 96 Suppl 1, S90-S95 (2013-06-04)
Mindfulness meditation is a method to relax the mind that decreases stress, which otherwise would increase serum cortisol. So, mindfulness meditation should decrease serum cortisol. To study the effect of mindfulness meditation on mental health by using Thai GHQ28 questionaire
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