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Merck

840475P

Avanti

18:1 (Δ9-Cis) PG

Avanti Research - A Croda Brand

Sinónimos:

1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1′racglycerol) (sodium salt); DOPG; PG(18:1(9Z)/18:1(9Z))

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About This Item

Fórmula empírica (notación de Hill):
C42H78O10PNa
Número de CAS:
Peso molecular:
797.03
Número MDL:
Código UNSPSC:
51191904
NACRES:
NA.25

descripción

1,2-dioleoyl-sn-glycero-3-phospho-(1′-rac-glycerol) (sodium salt)

Ensayo

>99% (TLC)

Formulario

powder

envase

pkg of 1 × 1 g (840475P-1g)
pkg of 2 × 100 mg (840475P-200mg)
pkg of 5 × 100 mg (840475P-500mg)
pkg of 1 × 25 mg (840475P-25mg)

fabricante / nombre comercial

Avanti Research - A Croda Brand

tipo de lípido

cardiolipins
phospholipids

Condiciones de envío

dry ice

temp. de almacenamiento

−20°C

cadena SMILES

[H][C@@](COP([O-])(OCC(O)CO)=O)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCC/C=C\CCCCCCCC)=O.[Na+]

InChI

1S/C42H79O10P.Na/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-41(45)49-37-40(38-51-53(47,48)50-36-39(44)35-43)52-42(46)34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2;/h17-20,39-40,43-44H,3-16,21-38H2,1-2H3,(H,47,48);/q;+1/p-1/b19-17-,20-18-;/t39?,40-;/m

Clave InChI

IUVFCFQZFCOKRC-IPKKNMRRSA-M

Descripción general

Phosphoglyceride (PG) are also referred as glycerophospholipid. It is an important component of membrane bilayers. It has three-carbon backbone of glycerol, two long-chain fatty acids, esterified to hydroxyl groups on carbons 1 and 2 of the glycerol and phosphoric acid esterified to the C3 hydroxyl group of glycerol. It is found at high levels in the membranes of all cells and at low levels in fat stores. 1,2-dioleoyl-sn-glycero-3-phospho-(1′-rac-glycerol) (DOPG)/18:1 (Δ9-Cis) PG has two hydroxyl groups in its head group. It is an anionic lipid.

Aplicación

18:1 (Δ9-Cis) PG has been used:
  • in the preparation of giant unilamellar vesicle (GUV)
  • in the preparation 200 nm large unilamellar vesicles (LUV)
  • as a supplement in native macrophage membranes to generate membrane liposomes with an artificially modified electrical charge

Acciones bioquímicas o fisiológicas

Phosphoglycerides (PG)/glycerophospholipids play a key role in cell signaling systems. It also serves as an anchor for proteins in cell membranes.

Envase

5 mL Clear Glass Sealed Ampule (840475P-200mg)
5 mL Clear Glass Sealed Ampule (840475P-25mg)
5 mL Clear Glass Sealed Ampule (840475P-500mg)
60 mL Amber Wide Mouth Screw Cap Glass Bottle (840475P-1g)

Información legal

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 3


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