840475P

18:1 (Δ9-Cis) PG

Avanti Research^™ - A Croda Brand

• Sinónimos: 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1′racglycerol) (sodium salt); DOPG; PG(18:1(9Z)/18:1(9Z))
• Fórmula empírica (notación de Hill): C₄₂H₇₈O₁₀PNa
• Número de CAS: 67254-28-8
• Peso molecular: 797.03
• MDL number: MFCD33403202
• UNSPSC Code: 51191904
• NACRES: NA.25

Propiedades

• description: 1,2-dioleoyl-sn-glycero-3-phospho-(1′-rac-glycerol) (sodium salt)
• assay: >99% (TLC)
• form: powder
• packaging: pkg of 1 × 1 g (840475P-1g); pkg of 2 × 100 mg (840475P-200mg); pkg of 5 × 100 mg (840475P-500mg); pkg of 1 × 25 mg (840475P-25mg)
• manufacturer/tradename: Avanti Research^™ - A Croda Brand
• lipid type: cardiolipins; phospholipids
• shipped in: dry ice
• storage temp.: −20°C
• SMILES string: [H][C@@](COP([O-])(OCC(O)CO)=O)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCC/C=C\CCCCCCCC)=O.[Na+]
• InChI: 1S/C42H79O10P.Na/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-41(45)49-37-40(38-51-53(47,48)50-36-39(44)35-43)52-42(46)34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2;/h17-20,39-40,43-44H,3-16,21-38H2,1-2H3,(H,47,48);/q;+1/p-1/b19-17-,20-18-;/t39?,40-;/m
• Inchi Key: IUVFCFQZFCOKRC-IPKKNMRRSA-M

Descripción

General description

Phosphoglyceride (PG) are also referred as glycerophospholipid. It is an important component of membrane bilayers. It has three-carbon backbone of glycerol, two long-chain fatty acids, esterified to hydroxyl groups on carbons 1 and 2 of the glycerol and phosphoric acid esterified to the C3 hydroxyl group of glycerol.[1] It is found at high levels in the membranes of all cells and at low levels in fat stores.[2] 1,2-dioleoyl-sn-glycero-3-phospho-(1′-rac-glycerol) (DOPG)/18:1 (Δ9-Cis) PG has two hydroxyl groups in its head group. It is an anionic lipid.[3]

Application

18:1 (Δ9-Cis) PG has been used:

• in the preparation of giant unilamellar vesicle (GUV)[4]
• in the preparation 200 nm large unilamellar vesicles (LUV)[5]
• as a supplement in native macrophage membranes to generate membrane liposomes with an artificially modified electrical charge[6]

Biochem/physiol Actions

Phosphoglycerides (PG)/glycerophospholipids play a key role in cell signaling systems. It also serves as an anchor for proteins in cell membranes.[2]

Packaging

5 mL Clear Glass Sealed Ampule (840475P-200mg)

5 mL Clear Glass Sealed Ampule (840475P-25mg)

5 mL Clear Glass Sealed Ampule (840475P-500mg)

60 mL Amber Wide Mouth Screw Cap Glass Bottle (840475P-1g)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Información de seguridad

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3