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ALD01804

Sigma-Aldrich

3-((4-chlorophenyl)amino)-3-methylbutan-1-ol

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About This Item

UNSPSC Code:
12352200
PubChem Substance ID:
329772792
NACRES:
NA.22

form

liquid

storage temp.

2-8°C

SMILES string

CC(CCO)(C)NC1=CC=C(Cl)C=C1

Application

Traditionally challenging to access, this hindered amine provides a chemically differentiated building block for organic synthesis and medicinal chemistry, specifically for preparation of drug candidates containing hindered amine motifs. Additionally, this and over 80 other sterically hindered secondary amines in the Sigma-Aldrich portfolio provide structurally distinct screening compounds. Screen several through Aldrich Market Select. This hindered amine was accessed via a recent publication reported by Baran and coworkers using an innovative hydroamination method.

Other Notes

Product of KemXTree
Practical olefin hydroamination with nitroarenes

Related product

Referencia del producto
Descripción
Precios

ALD01638

4-(methylthio)-N-(2, 4, 4 trimethylpentan-2-yl)aniline

ALD01640

N-(2,3-dimethylbutan-2-yl)-4-(methylthio) aniline

ALD01642

N-(4-(tert-butylamino)phenyl) acetamide

ALD01648

3-methyl-3-((perfluorophenyl) amino)butan-1-ol

ALD01652

2-methoxy-N-(1-methylcyclohexyl) pyridin-3-amine

ALD01654

3-((2-methoxypyridin-3-yl) amino)-3-methylbutan-1-ol

ALD01658

3-((2-chlorophenyl) amino)-3-methylbutan-1-ol

ALD01660

3-((9H-fluoren-2-yl)amino)-3-methylbutan-1-ol

ALD01662

N-(4-(benzyloxy)-2-methylbutan-2-yl)-9H-fluoren-2-amine

ALD01666

N-(2-methylpentan-2-yl)pyridin-3-amine

ALD01670

3-methyl-3-((4-(trifluoromethyl)phenyl)amino)butan-1-ol

ALD01672

N-(1-(benzyloxy)-2-methylpropan-2-yl)-4-(trifluoromethyl)aniline

ALD01688

4-methoxy-N-(tert-pentyl)aniline

ALD01702

N-(4-((4-hydroxy-2-methylbutan-2-yl)amino)phenyl)acetamide

ALD01736

3-(N-acetyl)-N-(tert-pentyl)aniline

ALD01742

N-(1,1-dimethylethyl)-1-Naphthalenamine

ALD01766

N-(tert-butyl)-4-methoxyaniline

ALD01784

N-(tert-butyl)-2-methoxypyridin-3-amine

ALD01818

4-(tert-butylamino)benzamide

ALD00588

N-(1-methylcyclohexyl)-4-(methylthio)aniline

ALD00590

N-(3-(tert-butylamino)phenyl)acetamide

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H317

pcodes

P280

Hazard Classifications

Skin Sens. 1

Storage Class

10 - Combustible liquids

flash_point_f

Not applicable

flash_point_c

Not applicable

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Contenido relacionado

Baran Group – Professor Product Portal

The Baran Group works with Sigma-Aldrich in providing a portfolio of zinc-based reagents promoting difluoromethylation, trifluoromethylation, trifluoroethylation and isopropylation of aryl and heteroaryl motifs. Baran’s lab has also helped introduce a portable desaturase (Tz0Cl), which promotes the installation of alcohol and amine groups and leaves behind a highly useful tosyl group for further transformations.

Nuestro equipo de científicos tiene experiencia en todas las áreas de investigación: Ciencias de la vida, Ciencia de los materiales, Síntesis química, Cromatografía, Analítica y muchas otras.

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