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Merck
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900741

Sigma-Aldrich

Gelatin methacryloyl

gel strength 170-195 g Bloom, degree of substitution: 60%

Sinónimos:

GelMA, Gelatin methacrylamide, Gelatin methacrylate, GelMa, Gelatin Methacrylate

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About This Item

Fórmula lineal:
(C40H59N11O13)n
UNSPSC Code:
12162002
NACRES:
NA.23

Quality Level

100

form

solid

storage temp.

2-8°C

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Application

Gelatin methacrylate can be used to form cross-linked hydrogels for tissue engineering and 3D printing. It has been used for endothelial cell morphogenesis, cardiomyocytes, epidermal tissue, injectable tissue constructs, bone differentiation, and cartilage regeneration. Gelatin methacrylate has been explored in drug delivery applications in the form of microspheres and hydrogels.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificados de análisis (COA)

Lot/Batch Number
MKCP1900
MKCD5518

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Facile one-step micropatterning using photodegradable methacrylated gelatin hydrogels for improved cardiomyocyte organization and alignment.
Tsang K, et al.
Advances in Functional Materials, 25(6), 977-986 (2015)
Photocrosslinkable gelatin hydrogel for epidermal tissue engineering.
Zhao X, et al.
Advanced Helathcare Materials (2015)
Covalent attachment of a three-dimensionally printed thermoplast to a gelatin hydrogel for mechanically enhanced cartilage constructs.
Boere KWM, et al.
Acta Biomaterialia, 10(6), 2602-2611 (2014)
Jason W Nichol et al.
Biomaterials, 31(21), 5536-5544 (2010-04-27)
The cellular microenvironment plays an integral role in improving the function of microengineered tissues. Control of the microarchitecture in engineered tissues can be achieved through photopatterning of cell-laden hydrogels. However, despite high pattern fidelity of photopolymerizable hydrogels, many such materials
Anh H Nguyen et al.
Acta biomaterialia, 13, 101-110 (2014-12-03)
Gelatin has been commonly used as a delivery vehicle for various biomolecules for tissue engineering and regenerative medicine applications due to its simple fabrication methods, inherent electrostatic binding properties, and proteolytic degradability. Compared to traditional chemical cross-linking methods, such as
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Artículos

Photo-Crosslinkable Gelatin Hydrogel: Versatile Materials for (High Resolution) Additive Manufacturing

Discussion of synthetic modifications to gelatin, improving the three-dimensional (3D) print resolution, and resulting material properties.

Three-Dimensional Bioprinting for Tissue and Disease Modeling

Professor Shrike Zhang (Harvard Medical School, USA) discusses advances in 3D-bioprinted tissue models for in vitro drug testing, reviews bioink selections, and provides application examples of 3D bioprinting in tissue model biofabrication.

Three-Dimensional Bioprinting for Tissue and Disease Modeling

Professor Shrike Zhang (Harvard Medical School, USA) discusses advances in 3D-bioprinted tissue models for in vitro drug testing, reviews bioink selections, and provides application examples of 3D bioprinting in tissue model biofabrication.

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Tissue engineering fabricates tissues cultures from scaffolds, living cells, and biologically active molecules by simulating the microenvironment of the body to repair or replace damaged tissue.

Tissue Engineering

Tissue engineering fabricates tissues cultures from scaffolds, living cells, and biologically active molecules by simulating the microenvironment of the body to repair or replace damaged tissue.

Ingeniería de tejidos

En la ingeniería de tejidos se fabrican cultivos de tejidos a partir de armazones, células vivas y moléculas biológicamente activas simulando el microentorno del organismo para reparar o sustituir tejido dañado.

Ingeniería de tejidos

En la ingeniería de tejidos se fabrican cultivos de tejidos a partir de armazones, células vivas y moléculas biológicamente activas simulando el microentorno del organismo para reparar o sustituir tejido dañado.

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