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900598

Sigma-Aldrich

(4-(Bromomethyl)phenyl)(4-(prop-2-yn-1-yloxy)phenyl)methanone

≥95%

Sinónimos:

Bromo benzophenone alkyne, Probe building block

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About This Item

Fórmula empírica (notación de Hill):
C17H13BrO2
Número de CAS:
1695554-80-3
Peso molecular:
329.19
MDL number:
MFCD30737994
UNSPSC Code:
12352200
NACRES:
NA.22

Quality Level

100

assay

≥95%

form

solid

reaction suitability

reaction type: click chemistry

storage temp.

−20°C

SMILES string

O=C(C1=CC=C(OCC#C)C=C1)C2=CC=C(CBr)C=C2

Application

Used for chemical probe synthesis, this trifunctional building block contains a light-activated benzophenone, alkyne tag, and bromine synthetic handle. When appended to a ligand or pharmacophore through its brominated linker, this building block allows for UV light-induced covalent modification of a biological target with potential for downstream applications via the alkyne tag. Use alone or in parallel with other multi-functional building blocks to discover the optimal probe for your chemical biology experiments.

Other Notes


Technology Spotlight: Trifuctional Probe Building Blocks

Development of Sulfonamide Photoaffinity Inhibitors for Probing Cellular γ-Secretase

A library approach to rapidly discover photoaffinity probes of the mRNA decapping scavenger enzyme DcpS

Related product

Referencia del producto
Descripción
Precios

900603

(4-(2-(2-Aminoethoxy)ethoxy)phenyl)(4-(prop-2-yn-1-yloxy)phenyl)methanone, ≥95%

900600

3-(Fluorosulfonyl)-5-((trimethylsilyl)ethynyl)benzoic acid, ≥95%

900601

3-Formyl-5-((trimethylsilyl)ethynyl)benzenesulfonyl fluoride, ≥95%

900602

4-(4-(Prop-2-yn-1-yloxy)benzoyl)benzoic acid, ≥95%

900605

3-(Bromomethyl)-5-((trimethylsilyl)ethynyl)benzenesulfonyl fluoride, ≥95%

900615

(4-Hydroxyphenyl)(4-(prop-2-yn-1-yloxy)phenyl)methanone, ≥95%

900614

3-(4-(Prop-2-yn-1-yloxy)benzoyl)benzoic acid, ≥95%

900613

5-(4-(4-(Prop-2-yn-1-yloxy)benzoyl)phenoxy)pentanoic acid, ≥95%

900611

(3-Hydroxyphenyl)(4-(prop-2-yn-1-yloxy)phenyl)methanone, ≥95%

900610

Hydroxyl di-benzophenone (PEG)3 alkyne

900619

4-(4-(Prop-2-yn-1-yloxy)benzoyl)benzaldehyde, ≥95%

900616

3-(But-3-yn-1-yl)-3-(2-iodoethyl)-3H-diazirine, ≥95%

900618

3-(3-(Bromomethyl)-5-ethynylphenyl)-3-(trifluoromethyl)-3H-diazirine, 95%

900683

2-(3-(But-3-yn-1-yl)-3H-diazirin-3-yl)ethan-1-amine, 95%

900750

(4-(2-(2-(2-Aminoethoxy)ethoxy)ethoxy)phenyl)(4-(prop-2-yn-1-yloxy)phenyl)methanone HCl salt, ≥95%

900831

3-(3-(But-3-yn-1-yl)-3H-diazirin-3-yl)propanoic acid

900848

4-Amino-2-trimethylsilanylethynyl-benzenesulfonyl fluoride

900847

4-(Fluorosulfonyl)-3-((trimethylsilyl)ethynyl)benzoic acid, ≥95%

900858

2-(Prop-2-yn-1-yloxy)-4-(3-(trifluoromethyl)-3H-diazirin-3-yl)benzoic acid, ≥95%

900860

3-Amino-5-ethynylbenzenesulfonyl fluoride, ≥95%

900862

(4-(3-(Trifluoromethyl)-3H-diazirin-3-yl)-2-((trimethylsilyl)ethynyl)phenyl)methanol

900859

3-Bromo-5-((trimethylsilyl)ethynyl)benzenesulfonyl fluoride, ≥95%

900863

2-(3-But-3-ynyl-3H-diazirin-3-yl)-ethanol, ≥95%

900864

4-(Bromomethyl)-2-((trimethylsilyl)ethynyl)benzenesulfonyl fluoride, ≥95%

900865

4-Formyl-2-((trimethylsilyl)ethynyl)benzenesulfonyl fluoride, ≥95%

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificados de análisis (COA)

Lot/Batch Number
MKCV6543
MKCS8812
MKCN4798
MKCC5517

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Artículos

Trifunctional Probe Building Blocks

In partnership with Pfizer chemists, we have compiled a collection of trifunctional building blocks to enable development of probes.

Trifunctional Probe Building Blocks

In partnership with Pfizer chemists, we have compiled a collection of trifunctional building blocks to enable development of probes.

Trifunctional Probe Building Blocks

In partnership with Pfizer chemists, we have compiled a collection of trifunctional building blocks to enable development of probes.

Trifunctional Probe Building Blocks

In partnership with Pfizer chemists, we have compiled a collection of trifunctional building blocks to enable development of probes.

Nuestro equipo de científicos tiene experiencia en todas las áreas de investigación: Ciencias de la vida, Ciencia de los materiales, Síntesis química, Cromatografía, Analítica y muchas otras.

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