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739952

Sigma-Aldrich

Resomer® RG 503, Poly(D,L-lactide-co-glycolide)

lactide:glycolide 50:50, ester terminated, Mw 24,000-38,000

Sinónimos:

PLGA, RESOMER® RG 503

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About This Item

Fórmula lineal:
[C3H4O2]x[C2H2O2]y
Número de CAS:
26780-50-7
Número MDL:
MFCD00131930
Código UNSPSC:
12162002
NACRES:
NA.23

Nivel de calidad

100

Formulario

amorphous

cociente alimentación

lactide:glycolide 50:50

mol peso

Mw 24,000-38,000

marco temporal de la degradación

<3 months

viscosidad

0.32-0.44 dL/g, 0.1 % (w/v) in chloroform(25 °C, Ubbelohde) (size 0c glass capillary viscometer)

temperatura de transición

Tg 44-48 °C

temp. de almacenamiento

2-8°C

cadena SMILES

O2C(C(=O)OC(C2=O)C)C.O1CC(=O)OCC1=O

InChI

1S/C6H8O4.C4H4O4/c1-3-5(7)10-4(2)6(8)9-3;5-3-1-7-4(6)2-8-3/h3-4H,1-2H3;1-2H2

Clave InChI

LCSKNASZPVZHEG-UHFFFAOYSA-N

Categorías relacionadas

Aplicación

Controlled release

Información legal

Product of Evonik
RESOMER is a registered trademark of Evonik Rohm GmbH

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

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Certificados de análisis (COA)

Lot/Batch Number
MKCW8517
BCCH9991
BCCG5990
BCCF1461
BCCB5545

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Kaiping Wang et al.
Journal of microencapsulation, 36(4), 356-370 (2019-06-14)
Here, we have successfully synthesised and purified multifunctional PLGA-based nanoparticles by the co-encapsulation of an anticancer drug (tetrandrine) and a magnetic material (Fe3O4). The obtained Tet-Fe3O4-PLGA NPs had a uniform spherical shape with a particle size of approximately 199 nm and
William A Lackington et al.
Journal of controlled release : official journal of the Controlled Release Society, 304, 51-64 (2019-05-06)
Neurotrophic factor delivery via biodegradable nerve guidance conduits may serve as a promising treatment for the repair of large peripheral nerve defects. However, a platform for controlled delivery is required because of their short in vivo half-life and their potential
Teresa Musumeci et al.
International journal of pharmaceutics, 440(2), 135-140 (2012-10-20)
Melatonin, a neurohormone secreted by the pineal gland, is able to modulate intraocular pressure (IOP). The aim of this study was to generate nanoparticle (NPs) sustained release formulations that allow to extend the pre-corneal residence time of melatonin, thus prolonging
Maria Kirzhner et al.
Ophthalmology, 120(6), 1300-1304 (2013-02-13)
To compare wrapped and polymer-coated hydroxyapatite implants in children undergoing primary enucleation with no adjuvant therapies. Retrospective, interventional cohort study. All children undergoing primary enucleation without adjuvant therapies between 1999 and 2009 at a tertiary pediatric cancer hospital. Review and
Kyle E Broaders et al.
Proceedings of the National Academy of Sciences of the United States of America, 106(14), 5497-5502 (2009-03-27)
Materials that combine facile synthesis, simple tuning of degradation rate, processability, and biocompatibility are in high demand for use in biomedical applications. We report on acetalated dextran, a biocompatible material that can be formed into microparticles with degradation rates that
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