658235

Lithium dimethylaminoborohydride solution

1 M in THF

• Sinónimos: N-Methylmethanamine boron complex, Lithium (dimethylamino)trihydroborate, Lithium trihydro(N-methylmethanaminato)borate
• Fórmula empírica (notación de Hill): C₂H₉BLiN
• Número de CAS: 53042-33-4
• Peso molecular: 64.85
• MDL number: MFCD07784404
• UNSPSC Code: 12352000
• PubChem Substance ID: 24884338
• NACRES: NA.22

Propiedades

• reaction suitability: reagent type: reductant
• Quality Level: 100
• concentration: 1 M in THF
• refractive index: n20/D 1.423
• density: 0.882 g/mL at 25 °C
• storage temp.: 2-8°C
• SMILES string: [Li+].[BH3-]N(C)C
• InChI: 1S/C2H9BN.Li/c1-4(2)3;/h1-3H3;/q-1;+1
• InChI key: CEDUMRZWZLVFKS-UHFFFAOYSA-N

Descripción

General description

Lithium dimethylaminoborohydride is a reagent exhibiting dual properties like a metal hydride and nitrogen nucleophile. It is generally considered as an alternative to lithium aluminum hydride (LAH) for the reduction of carbonyl compounds, amides, and lactams.

Application

Lithium Aminoborohydride (LAB) Reagents

Reactant for:

• B-H oxidative addition reactions
• Reduction and amination reactions
• Reduction of N-alkyl lactams
• Synthesis of tertiary amine-boranes

Capable of reducing a variety of fuctional groups.

LABs can transfer the amine moiety, as in the case of the reaction with halopyridines and primary alkyl methanesulfonates.

Información de seguridad

• pictograms: GHS02,GHS08,GHS07
• signalword: Danger
• hcodes: H225,H302,H319,H335,H351
• pcodes: P210 - P280 - P301 + P312 + P330 - P305 + P351 + P338 - P370 + P378 - P403 + P235
• Hazard Classifications: Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Flam. Liq. 2 - STOT SE 3
• target_organs: Respiratory system
• supp_hazards: EUH019
• Storage Class: 4.3 - Hazardous materials which set free flammable gases upon contact with water
• wgk_germany: WGK 3
• flash_point_f: 1.4 °F - closed cup
• flash_point_c: -17 °C - closed cup