480959
Glycolamide
98%
Sinónimos:
2-Hydroxyacetamide
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About This Item
Productos recomendados
Quality Level
assay
98%
mp
118-120 °C (lit.)
functional group
amide
hydroxyl
SMILES string
NC(=O)CO
InChI
1S/C2H5NO2/c3-2(5)1-4/h4H,1H2,(H2,3,5)
InChI key
TZGPACAKMCUCKX-UHFFFAOYSA-N
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General description
Glycolamide, an isomer of glycine, can be synthesized by the ammonolysis of ethyl glycolate. The conformational analysis of glycolamide has been reported. Its diffusion coefficient in water and partial molal isothermal compressibility has been determined. Its thermodynamic properties have been investigated. Its osmotic and activity coefficients have been obtained.
Application
Glycolamide may be used in the preparation of phosphoglycolamide.
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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European journal of medicinal chemistry, 44(1), 289-295 (2008-04-26)
On the basis of the structural similarity of N-substituted glycolamides with N-glycolyl muramic acid residues of the cell wall of Mycobacterium tuberculosis, a series of these compounds were designed and synthesized by the reaction of glycolic acid acetonide 1 (2,2-dimethyl-5-oxo-1,3-dioxolane)
Partial molal isothermal compressibility of glycine, DL-α-alanine, glycylglycine, glycolamide, and lactamide.
The Journal of Physical Chemistry, 97(49), 13027-13028 (1993)
Drug development and industrial pharmacy, 27(1), 63-70 (2001-03-15)
Glycolamide esters of ibuprofen (I), namely, unsubstituted (II), N,N dimethyl (III), and N,N diethyl (IV), were synthesized and studied for different physicochemical, pharmacological, and toxicological properties. They were comparable with I in respect of anti-inflammatory and analgesic activity but did
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Complexation of Pu(IV) with TMDGA, TEDGA, and TODGA diglycolamide ligands was followed by vis-NIR spectroscopy. A crystal structure determination reveals that TMDGA forms a 1 : 3 homoleptic Pu(IV) complex with the nitrate anions forced into the outer coordination sphere.
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