394963

N,N-Dimethylformamide dimethyl acetal

for GC derivatization, LiChropur^™

• Sinónimos: 1,1-Dimethoxy-N,N-dimethylmethylamine, 1,1-Dimethoxytrimethylamine
• Fórmula lineal: (CH₃)₂NCH(OCH₃)₂
• Número de CAS: 4637-24-5
• Peso molecular: 119.16
• Beilstein: 506020
• Número CE: 225-063-3
• Número MDL: MFCD00008482
• Código UNSPSC: 12000000
• ID de la sustancia en PubChem: 24864631
• NACRES: NA.22

Propiedades

• grado: for GC derivatization
• Nivel de calidad: 100
• Ensayo: >95%
• Formulario: liquid
• calidad: LiChropur^™
• idoneidad de la reacción: reagent type: derivatization reagent; reaction type: Acylations; reagent type: derivatization reagent; reaction type: Esterifications
• técnicas: gas chromatography (GC): suitable
• índice de refracción: n20/D 1.396 (lit.)
• bp: 102-103 °C/720 mmHg (lit.)
• densidad: 0.897 g/mL at 25 °C (lit.)
• cadena SMILES: COC(OC)N(C)C
• InChI: 1S/C5H13NO2/c1-6(2)5(7-3)8-4/h5H,1-4H3
• Clave InChI: ZSXGLVDWWRXATF-UHFFFAOYSA-N

Descripción

Descripción general

Esterate M (N,N-Dimethylformamide dimethyl acetal, DMFDMA) is an methylating reagent. It has been used in methyl esterification of carboxylic acid and also in one-step derivatization of amino acids into N,N-Dimethylaminomethylene methyl esters.[1]

Aplicación

It may be used in methylation of heterocyclic compounds which contains SH, NH, OH groups such as benzimidazole, naphth[2,3-c]imidazole, imidazo[4,5-c]-pyridine, purine, pyridine, pyrimidine, pyridazine and s-triazolo[4,3-b]pyridazine.[2] It was used as derivatizing agent in a study to determine cocaine and benzoyl ecgonine in urine using GC with on-column alkylation.[3]

Suitable for the derivatization of primary sulfonamides and trifluoroacetic acid.

Used in the preparation of formamidine derivatives,[4][5] which are synthetic intermediates.[6]

Used to catalyze the coupling of epoxides with carbon dioxide under solvent free conditions leading to cyclic carbonates.[7]

Otras notas

Reagent for n-dimethylaminomethylene and methyl esters.

Información legal

LiChropur is a trademark of Merck KGaA, Darmstadt, Germany

Información de seguridad

• Pictogramas: GHS02,GHS05,GHS07
• Palabra de señalización: Danger
• Frases de peligro: H225,H317,H318,H332
• Consejos de prudencia: P210 - P233 - P280 - P303 + P361 + P353 - P304 + P340 + P312 - P305 + P351 + P338
• Clasificaciones de peligro: Acute Tox. 4 Inhalation - Eye Dam. 1 - Flam. Liq. 2 - Skin Sens. 1
• Código de clase de almacenamiento: 3 - Flammable liquids
• Clase de riesgo para el agua (WGK): WGK 1
• Punto de inflamabilidad (°F): 42.8 °F
• Punto de inflamabilidad (°C): 6 °C
• Equipo de protección personal: Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter