37870
3-(2,4-Dihydroxyphenyl)propionic acid
≥95.0% (HPLC)
Sinónimos:
2,4-Dihydroxyhydrocinnamic acid, Hydroumbellic acid
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About This Item
Fórmula empírica (notación de Hill):
C9H10O4
Número de CAS:
Peso molecular:
182.17
Beilstein/REAXYS Number:
2694769
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22
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assay
≥95.0% (HPLC)
form
solid
mp
158-162 °C
functional group
carboxylic acid
SMILES string
OC(=O)CCc1ccc(O)cc1O
InChI
1S/C9H10O4/c10-7-3-1-6(8(11)5-7)2-4-9(12)13/h1,3,5,10-11H,2,4H2,(H,12,13)
InChI key
HMCMTJPPXSGYJY-UHFFFAOYSA-N
General description
3-(2,4-Dihydroxyphenyl)propionic acid is a 3,4-dihydroxyphenylalanine (DOPA) analog. It is a building block for heterocyclic compounds.
Application
3-(2,4-Dihydroxyphenyl)propionic acid (DHPPA) may be used as substrate for the o-diphenolase in microplate assays of serum and hemocyte supernatants from QXR3 and wild type oysters for the quantitation of o-diphenolase activity.
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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B Morin et al.
The Biochemical journal, 330 ( Pt 3), 1059-1067 (1998-05-23)
A major product of hydroxy-radical addition to tyrosine is 3, 4-dihydroxyphenylalanine (DOPA) which has reducing properties. Protein-bound DOPA (PB-DOPA) has been shown to be a major component of the stable reducing species formed during protein oxidation under several conditions. The
Kathryn Newton et al.
Developmental and comparative immunology, 28(6), 565-569 (2004-06-05)
QX is a fatal disease in Sydney rock oysters (Saccostrea glomerata) that results from infection by the protistan parasite, Marteilia sydneyi. Since 1997, the New South Wales Fisheries Service has bred S. glomerata for resistance to QX disease. The current
A new synthesis of psoralene [(author's transl)].
O Dann et al.
Archiv der Pharmazie, 308(2), 121-130 (1975-02-01)
Violetta Mohos et al.
Biomolecules, 10(3) (2020-03-12)
Flavonoids are abundant polyphenols in nature. They are extensively biotransformed in enterocytes and hepatocytes, where conjugated (methyl, sulfate, and glucuronide) metabolites are formed. However, bacterial microflora in the human intestines also metabolize flavonoids, resulting in the production of smaller phenolic
Violetta Mohos et al.
International journal of molecular sciences, 20(11) (2019-06-05)
Quercetin is an abundant flavonoid in nature and is used in several dietary supplements. Although quercetin is extensively metabolized by human enzymes and the colonic microflora, we have only few data regarding the pharmacokinetic interactions of its metabolites. Therefore, we
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