22490

Chelidamic acid hydrate

≥97.0% (dried material, T), ~1 mol/mol water

• Sinónimos: 1,4-Dihydro-4-oxo-2,6-pyridinedicarboxylic acid hydrate, 4-Hydroxypyridine-2,6-dicarboxylic acid
• Fórmula empírica (notación de Hill): C₇H₅NO₅ · xH₂O
• Número de CAS: 138-60-3
• Peso molecular: 183.12 (anhydrous basis)
• Beilstein/REAXYS Number: 476229
• EC Number: 205-335-8
• MDL number: MFCD03818117
• UNSPSC Code: 12352100
• PubChem Substance ID: 57647988
• NACRES: NA.22

Propiedades

• assay: ≥97.0% (dried material, T)
• form: powder
• impurities: ~1 mol/mol water
• mp: 267 °C (dec.) (lit.)
• functional group: carboxylic acid
• SMILES string: O.OC(=O)C1=CC(=O)C=C(N1)C(O)=O
• InChI: 1S/C7H5NO5.H2O/c9-3-1-4(6(10)11)8-5(2-3)7(12)13;/h1-2H,(H,8,9)(H,10,11)(H,12,13);1H2
• InChI key: SNGPHFVJWBKEDG-UHFFFAOYSA-N

Descripción

Application

Chelidamic acid hydrate was used in the synthesis of 4-Chloro-N,N,N′,N′-tetraethylpyridine-2,6-dicarboxamide.

Biochem/physiol Actions

Among the most potent of the tested "conformationally restricted glutamate analogs" as an inhibitor of glutamate decarboxylase.

Información de seguridad

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319,H335
• pcodes: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves