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Merck

120618

Sigma-Aldrich

4-Hydroxypyridine

95%

Sinónimos:

4-Pyridinol, 4-Pyridone

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About This Item

Fórmula empírica (notación de Hill):
C5H5NO
Número de CAS:
Peso molecular:
95.10
Beilstein/REAXYS Number:
105800
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Quality Level

assay

95%

bp

230-235 °C/12 mmHg (lit.)

mp

150-151 °C (lit.)

SMILES string

O=C1C=CNC=C1

InChI

1S/C5H5NO/c7-5-1-3-6-4-2-5/h1-4H,(H,6,7)

InChI key

GCNTZFIIOFTKIY-UHFFFAOYSA-N

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Application

4-Hydroxypyridine was used in the synthesis of (Ag3MoO3F3) (Ag3MoO4)Cl by hydro(solvato)thermal methods. It was used as model compound to study the natural photodegradation of representative aquatic environmental contaminants.

pictograms

CorrosionExclamation mark

signalword

Danger

Hazard Classifications

Acute Tox. 4 Oral - Eye Dam. 1 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


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H Chen et al.
Biochemistry, 32(43), 11591-11599 (1993-11-02)
We have examined the interaction of Citrobacter freundii tyrosine phenol-lyase with both L- and D-alanine. This enzyme catalyzes the racemization of alanine as a side reaction, in addition to the physiological beta-elimination of L-tyrosine to give phenol and ammonium pyruvate.
Modelling the natural photodegradation of water contaminants: a kinetic study on the light-induced aerobic interactions between riboflavin and 4-hydroxypyridine.
Pajares A, et al.
J. Photochem. Photobiol., A, 139(2), 199-204 (2001)
Heiko Zettl et al.
ACS chemical biology, 7(9), 1488-1495 (2012-06-26)
We present an integrated approach to identify and optimize a novel class of γ-secretase modulators (GSMs) with a unique pharmacological profile. Our strategy included (i) virtual screening through application of a recently developed protocol (PhAST), (ii) synthetic chemistry to discover
Natsuki K Kubota et al.
Bioorganic & medicinal chemistry, 11(21), 4569-4575 (2003-10-07)
Piericidins C5 (1) and C6 (2), two new members of the piericidin family, were isolated from a Streptomyces sp. and a Nocardioides sp., together with known piericidins C1 (3), C2 (4), C3 (5), C4 (6), D1 (7), and A3 (8).
G P Carlson
Toxicology letters, 85(3), 173-178 (1996-06-01)
In order to evaluate the possibility that the metabolism of pyridine may be important for its toxic actions, pyridine was compared with pyridine N-oxide, 2-hydroxypyridine, 3-hydroxypyridine, 4-hydroxypyridine and pyridinium methyliodide in rats given equal molar doses of the chemicals i.p.

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