Peptide dendrimer-conjugates of ketoprofen: Synthesis and ex vivo and in vivo evaluations of passive diffusion, sonophoresis and iontophoresis for skin delivery.

Peptide dendrimer-conjugates of ketoprofen: Synthesis and ex vivo and in vivo evaluations of passive diffusion, sonophoresis and iontophoresis for skin delivery.

European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences (2017-03-13)

Aswathi R Hegde, Prarthana V Rewatkar, Jyothsna Manikkath, Karnaker Tupally, Harendra S Parekh, Srinivas Mutalik

摘要

The aim of this study was to evaluate skin delivery of ketoprofen when covalently tethered to mildly cationic (2

材料

货号

品牌

产品描述

Sigma-Aldrich

三异丙基硅烷, 98%

Sigma-Aldrich

苯并三氮唑-N,N,N′,N′-四甲基脲六氟磷酸酯, ≥98.0% (T)

Sigma-Aldrich

Fmoc-Lys(Fmoc)-OH, ≥98.0% (HPLC)