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Merck
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文件

1592409

USP

槲皮素

United States Pharmacopeia (USP) Reference Standard

别名:

槲皮素 二水合物, 2-（3,4-二羟基苯基）-3,5,7-三羟基-4 H -1-苯并吡喃-4-酮 二水合物, 3,3′,4′,5,7-五羟基黄酮 二水合物

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About This Item

经验公式（希尔记法）:
C15H10O7 · 2H2O
CAS号:
6151-25-3
分子量:
338.27
顏色索引編號:
75670
Beilstein:
317313
分類程式碼代碼:
41116107
NACRES:
NA.24

等級

pharmaceutical primary standard

API 家族

quercetin

製造商／商標名

USP

mp

>300 °C (lit.)

應用

pharmaceutical (small molecule)

格式

neat

儲存溫度

−20°C

SMILES 字串

OC(C(O)=C1)=CC=C1C2=C(O)C(C3=C(O)C=C(O)C=C3O2)=O

InChI

1S/C15H10O7.2H2O/c16-7-4-10(19)12-11(5-7)22-15(14(21)13(12)20)6-1-2-8(17)9(18)3-6;;/h1-5,16-19,21H;2*1H2

InChI 密鑰

GMGIWEZSKCNYSW-UHFFFAOYSA-N

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一般說明

本产品按照发行药典的发行和规定提供。支持本产品的所有信息，包括安全数据表和任何产品信息传单，都是在发行药典的授权下开发和发布的。有关更多信息和支持，请访问发行药典的网站。

應用

槲皮素USP参考标准品旨在用于USP药典规定的指定质量测试和分析。
也用于下列USP专论方法：
  • 蔓越橘果汁干提取物
  • 槐花
  • 槐花粉
  • 槐花芽
  • 槐花干提取物
  • 蔓越橘果汁干提取物胶囊
  • 芦丁

生化／生理作用

槲皮素二水合物是具有抗癌活性的黄酮类化合物。槲皮素为线粒体 ATP 酶和磷酸二酯酶抑制剂。它可抑制 PI3 激酶活性并且轻微抑制 PIP 激酶活性。槲皮素对癌细胞系具有抗增殖作用，通过 II 型雌激素受体降低癌细胞的生长，并且阻滞细胞周期晚期 G1 相中人类白血病 T 细胞。

分析報告

这些产品仅供测试和化验使用。它们不适用于人类或动物，也不能用于诊断、治疗或治愈任何类型的疾病。

其他說明

可能适用相应的销售限制。

相關產品

产品编号
说明
价格

象形圖

Skull and crossbones
GHS06

訊號詞

Danger

危險聲明

H301

危險分類

Acute Tox. 3 Oral

儲存類別代碼

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

水污染物質分類（WGK）

WGK 1

分析证书(COA)

输入产品批号来搜索 分析证书(COA) 。批号可以在产品标签上"批“ （Lot或Batch）字后找到。

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Chronic inflammatory events appear to play a fundamental role in Alzheimer's disease (AD)-related neuropathological changes, and to result in neuronal dysfunction and death. The inflammatory responses observed in the AD brain include activation and proliferation of glial cells, together with
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Two sets of carbamates based on the natural alkaloid evodiamine were designed, synthesized and evaluated as potential butyrylcholinesterase inhibitors. Although a set of carbamates of 3-hydroxyevodiamine (10a-f) is inactive both at AChE and BChE, carbamates of 5-deoxo-3-hydroxyevodiamine (11a-f) exhibit much
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This study demonstrated that 0.5% dietary rutin, ellagic acid, or curcumin markedly increased cecal succinate levels in rats fed a high-fat diet, whereas catechin, caffeic acid, and quercetin did not. Other organic acids were modestly or hardly affected by polyphenols.
Ouissame Bounedjah et al.
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The sequence of events leading to stress granule assembly in stressed cells remains elusive. We show here, using isotope labeling and ion microprobe, that proportionally more RNA than proteins are present in stress granules than in surrounding cytoplasm. We further
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