推荐产品
等级
pharmaceutical primary standard
API类
nifedipine
制造商/商品名称
USP
应用
pharmaceutical (small molecule)
包装形式
neat
SMILES字符串
O=C(OC)C1=C(C2=C(N=O)C=CC=C2)C(C(OC)=O)=C(C)N=C1C
InChI
1S/C17H16N2O5/c1-9-13(16(20)23-3)15(11-7-5-6-8-12(11)19-22)14(10(2)18-9)17(21)24-4/h5-8H,1-4H3
InChI key
MUZLTKGYFZENFW-UHFFFAOYSA-N
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一般描述
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.
应用
Nifedipine Nitrosophenylpyridine Analog USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
- Nifedipine
- Nifedipine Capsules
- Nifedipine Extended-Release Tablets
分析说明
These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.
其他说明
Sales restrictions may apply.
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产品编号
说明
价格
警示用语：
Warning
危险分类
Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
V Misík et al.
Molecular pharmacology, 40(3), 435-439 (1991-09-01)
Nifedipine [1,4-dihydro-2,6-dimethyl-4-(2-nitrophenyl)-3,5-pyridinedicarboxylic+ ++ acid dimethyl ester] and nimodipine [1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic+ ++ acid 2-methoxyethyl 1-methylethyl ester], incorporated into diheptanoylphosphatidylcholine liposomes, which were used as a drug carrier system, slightly inhibited lipid peroxidation (induced by tert-butylhydroperoxide and Fe2+) in rat heart homogenate. Illumination
Jürgen Schoppe et al.
Cell calcium, 33(3), 207-221 (2003-02-26)
Leech P neurons possess caffeine-sensitive ion channels in intracellular Ca(2+) stores and in the plasma membrane. The following results indicate that these channels are also activated by 2,6-dimethyl-4-(2-nitrosophenyl)-3,5-pyridinedicarboxylic acid dimethyl ester (NTP), the photoproduct of the L-type Ca(2+) channel-blocker nifedipine:
G Carlucci et al.
Farmaco (Societa chimica italiana : 1989), 45(6 Suppl), 751-755 (1990-06-01)
A method for the determination of 2,6-dimethyl-4-(2'-nitrosophenyl)-3,5-pyridinedicarboxylic acid dimethylester in nifedipine (bulk material and pharmaceutical formulations) by second-derivative ultraviolet spectrophotometry is described. The procedure is simple and rapid and gives accurate and precise results.
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