1269152

泛昔洛韦

United States Pharmacopeia (USP) Reference Standard

• 别名: 2-[2-(2-氨基-9H-嘌呤-9-基)乙基]-1,3-丙二醇二乙酸酯, BRL 42810
• 经验公式（希尔记法）: C₁₄H₁₉N₅O₄
• CAS号: 104227-87-4
• 分子量: 321.33
• MDL號碼: MFCD00866964
• 分類程式碼代碼: 41116107
• PubChem物質ID: 329749829
• NACRES: NA.24

属性

• 等級: pharmaceutical primary standard
• API 家族: famciclovir
• 製造商／商標名: USP
• 應用: pharmaceutical (small molecule)
• 格式: neat
• 儲存溫度: 2-8°C
• SMILES 字串: CC(=O)OCC(CCn1cnc2cnc(N)nc12)COC(C)=O
• InChI: 1S/C14H19N5O4/c1-9(20)22-6-11(7-23-10(2)21)3-4-19-8-17-12-5-16-14(15)18-13(12)19/h5,8,11H,3-4,6-7H2,1-2H3,(H2,15,16,18)
• InChI 密鑰: GGXKWVWZWMLJEH-UHFFFAOYSA-N

说明

一般說明

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

應用

Famciclovir USP Reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

• Famciclovir Tablets
• Famciclovir Compounded Oral Suspension

生化／生理作用

泛昔洛韦是一种抗逆转录病毒鸟苷类似物，用于治疗疱疹病毒感染和乙肝。泛昔洛韦可迅速转化为喷昔洛韦。病毒胸苷激酶将喷昔洛韦磷酸化为单磷酸形式，然后细胞激酶又将其转换为三磷酸喷昔洛韦。喷昔洛韦三磷酸可竞争性抑制病毒 DNA 聚合酶，从而抑制病毒复制。长时间服用会形成耐药性；这通常表现为筛选出了一批 DNA 聚合酶基因逆转录酶结构域突变的预先存在的耐药性菌株。

分析報告

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

其他說明

Sales restrictions may apply.

安全信息

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable