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一般說明
Carboxen是由高分子前体高度改性而成的人造碳吸附剂。这种粒子既不会像树脂一样发生塑性变形，也不会像活性炭一样产生细微颗粒。以干燥形式储运。Carboxen作为衍生树脂适合各种去除小分子和大分子杂质的纯化应用。气相和液相纯化皆可。包括，去除原料药(API)中的均相催化剂，在生化纯化中去除高风险杂质（如，单抗中的残留宿主细胞蛋白），去除重金属，纯化氯化物，去除可萃取物和可浸出物。大小不一的渐变孔径改善了吸附和解吸的热力学和动力学特性。Carboxen形式多样，具有不同的孔结构（微孔、中孔和大孔比例不同）、比表面积和表面pH。
應用
Carboxens® are a highly engineered synthetic carbon adsorbent engineered from polymeric precursors. These particles will not plastically deform like resins or generate fines like activated carbon. These materials are shipped and stored dried. These derivatized resins bring value to a wide range of purification applications for removing both small and large molecule impurities. They find use in both gas and liquid phase purifications. Some examples include removal of homogenous catalysts from active pharmaceutical ingredients (API)s, high-risk impurities in biochemical purifications such as host cell proteins from mAbs, removal of toxic heavy metals, purification of chlorinated molecules, and removal of extractables and leachables.
特點和優勢
特点及优势：
- 球形
- 坚硬，球盘硬度>98%
- 温度稳定性高达400°C
- 高纯度
- 易于填料
- 全pH范围下稳定
- 不产生背压
- 渗透压冲击稳定性高
- 渐变式孔径（从大孔到中孔再到微孔)
其他說明
有关更多信息，请访问：特种碳吸附剂
法律資訊
Carboxen isa registered trademark of Sigma-Aldrich Co. LLC
Carboxen is a registered trademark of Merck KGaA, Darmstadt, Germany
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
nwg
閃點（°F）
Not applicable
閃點（°C）
Not applicable
商品
Demonstration of the excellent capability of Carboxen® synthetic carbon adsorbents to reduce host cell proteins (HCPs) and recover monoclonal antibodies (mAbs) using a post protein A pool step.
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