推荐产品
product name
SUPELCOSIL ™ ABZ + Plus HPLC 色谱柱, 3 μm particle size, L × I.D. 10 cm × 2.1 mm
agency
suitable for USP L60
特點
endcapped
製造商／商標名
SUPELCOSIL™
標籤範圍
12.0% carbon loading
參數
≤70 °C temp. range
400 bar pressure (5801 psi)
技術
HPLC: suitable
長度 × 內徑
10 cm × 2.1 mm
表面積
170 m2/g
表面覆盖率
surface coverage 3.4 μmol/m2
基質
silica gel, spherical particle platform
基質活性組
amide, alkyl phase
粒徑
3 μm
孔徑
120 Å
pH值範圍
2-7.5
應用
food and beverages
分離技術
reversed phase
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相关类别
一般說明
SUPELCOSIL ABZ+Plus 色谱柱可提供高去活特性和独特的选择性。经失活处理的硅胶颗粒粒径均一，确保其具有高柱效和低背压。经过键合和封尾后，ABZ+Plus 键合相有效的屏蔽了残余硅羟基，阻止了残余硅羟基与大多数化合物间的相互作用，无论分析物基团的特性如何均可获得对称的峰形。该键合相也允许在流动相中使用低离子强度的缓冲溶液，无需添加离子抑制剂。ABZ+Plus 让您可以使用简单的流动相来进行最困难的化合物分析，无论酸、强碱性化合物还是两性离子均可轻松胜任。
按照美国药典 (USP) 适用于 L60
按照美国药典 (USP) 适用于 L60
特點和優勢
•对极性、非极性和带电荷分析物均具有很高的柱效
•对具有反应性的化合物也可获得对称性良好的峰形
•对极性和带电荷的化合物具有独特的选择性
•对具有反应性的化合物也可获得对称性良好的峰形
•对极性和带电荷的化合物具有独特的选择性
法律資訊
SUPELCOSIL is a trademark of Sigma-Aldrich Co. LLC
Zhongping John Lin et al.
Journal of pharmaceutical and biomedical analysis, 37(4), 757-762 (2005-03-31)
A highly sensitive method was developed and validated for determining the free fraction of flunarizine in human plasma. Equilibrium dialysis was used for the separation of free (unbound) drug and liquid chromatography/tandem mass spectrometry (LC-MS/MS) was used for quantitation. Post-dialysis
Tânia M G Almeida et al.
Chemistry & biodiversity, 2(12), 1691-1700 (2006-12-29)
Absorption, distribution, metabolism, and excretion (ADME) properties are of invaluable importance to a bioactive compound. Permeation process is one of the most widely studied by many different techniques. Among them, reversed-phase liquid chromatography (RP-LC) is proving to be of great
K Ary et al.
Journal of chromatography. A, 797(1-2), 221-226 (1998-05-16)
A reversed-phase high-performance liquid chromatographic method with electrochemical detection has been developed for the determination of buspirone from human plasma. The separation was carried out by using a Supelcosil ABZ+ plus C18 reversed-phase column and 0.05 M potassium dihydrogenphosphate (pH
W Pan et al.
Journal of chromatography. B, Biomedical sciences and applications, 703(1-2), 129-138 (1998-02-03)
A sensitive, specific and precise HPLC-UV assay was developed to quantitate cocaine (COC) and its metabolites benzoylecgonine (BE), norcocaine (NC) and cocaethylene (CE) in rat plasma. After adding 50 microl of the internal standard solution (bupivacaine, 8 microg/ml) and 500
A B Baranda et al.
Talanta, 67(5), 933-941 (2008-10-31)
A liquid-liquid extraction method using diethyl ether as organic solvent was optimized simultaneously for five 1,4-dihydropyridines (amlodipine, nitrendipine, felodipine, lacidipine and lercanidipine) belonging to the group of calcium channel blockers. Some experimental tools such as a full factorial design, a
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