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Merck

47774

Supelco

维生素 (K2)

analytical standard

别名:

维生素 K2, 四烯甲萘醌, 甲萘醌 4

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About This Item

经验公式(希尔记法):
C31H40O2
CAS号:
分子量:
444.65
MDL號碼:
分類程式碼代碼:
12164500
PubChem物質ID:

等級

analytical standard

CofA

current certificate can be downloaded

特點

standard type fat soluble vitamin

包裝

ampule of 100 mg

技術

HPLC: suitable
gas chromatography (GC): suitable

應用

pharmaceutical (small molecule)
vitamins, nutraceuticals, and natural products

格式

neat

儲存溫度

-10 to -25°C

SMILES 字串

C\C(C)=C\CC\C(C)=C\CC\C(C)=C\CC\C(C)=C\CC1=C(C)C(=O)c2ccccc2C1=O

InChI

1S/C31H40O2/c1-22(2)12-9-13-23(3)14-10-15-24(4)16-11-17-25(5)20-21-27-26(6)30(32)28-18-7-8-19-29(28)31(27)33/h7-8,12,14,16,18-20H,9-11,13,15,17,21H2,1-6H3/b23-14+,24-16+,25-20+

InChI 密鑰

DKHGMERMDICWDU-GHDNBGIDSA-N

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一般說明

甲基萘醌 (K2),一种维生素 K2 同系物,具有四个异戊二烯单元。有报道它能增强骨形成 ,对血液凝血因子的产生起至关重要的角色。

應用

有关合适仪器技术的更多信息,请参考产品的分析证书。如需进一步支持,请联系技术服务。
甲基萘醌可用作引用液相色谱串联质谱法测定人血浆中甲基萘醌的参比标准品。

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儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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分析证书(COA)

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Menatetrenone, a vitamin K2 analogue, inhibits hepatocellular carcinoma cell growth by suppressing cyclin D1 expression through inhibition of nuclear factor κ activation.
Ozaki I, et al.
Clinical Cancer Research, 13(7), 2236-2245 (2007)
Simple and sensitive determination of menatetrenone and its epoxide metabolite in human plasma.
Kang W, et al.
Journal of Pharmaceutical and Biomedical Analysis, 44(5), 1178-1182 (2007)
Effects of menatetrenone on bone loss induced by ovariectomy in rats.
Akiyama Y, et al.
Japanese Journal of Pharmacology, 62(2), 145-153 (1993)
Katheryne Z Edson et al.
Biochemistry, 52(46), 8276-8285 (2013-10-22)
Vitamin K plays an essential role in many biological processes including blood clotting, maintenance of bone health, and inhibition of arterial calcification. A menaquinone form of vitamin K, MK4, is increasingly recognized for its key roles in mitochondrial electron transport
Toshiro Sato et al.
Nutrition journal, 11, 93-93 (2012-11-13)
Vitamin K₂ contributes to bone and cardiovascular health. Therefore, two vitamin K₂ homologues, menaquinone-4 (MK-4) and menaquinone-7 (MK-7), have been used as nutrients by the food industry and as nutritional supplements to support bone and cardiovascular health. However, little is

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