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Merck

442687

Supelco

N-亚硝基二乙胺

analytical standard

别名:

二乙基亚硝胺

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About This Item

线性分子式:
(C2H5)2NNO
CAS号:
分子量:
102.14
Beilstein:
1744991
EC號碼:
MDL號碼:
分類程式碼代碼:
12000000
PubChem物質ID:

等級

analytical standard

CofA

current certificate can be downloaded

包裝

ampule of 1000 mg

技術

HPLC: suitable
gas chromatography (GC): suitable

bp

177 °C (lit.)

密度

0.95 g/mL (lit.)

應用

cleaning products
cosmetics
environmental
food and beverages
personal care

格式

neat

儲存溫度

2-30°C

SMILES 字串

CCN(CC)N=O

InChI

1S/C4H10N2O/c1-3-6(4-2)5-7/h3-4H2,1-2H3

InChI 密鑰

WBNQDOYYEUMPFS-UHFFFAOYSA-N

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應用

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象形圖

Skull and crossbonesHealth hazard

訊號詞

Danger

危險聲明

危險分類

Acute Tox. 3 Oral - Aquatic Chronic 3 - Carc. 1B

儲存類別代碼

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

水污染物質分類(WGK)

WGK 3

個人防護裝備

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter


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分析证书(COA)

Lot/Batch Number

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Masaaki Miyakoshi et al.
Molecular carcinogenesis, 53(1), 67-76 (2012-08-23)
STAT3 activation is involved in development and progression of hepatocellular carcinoma (HCC). We investigated STAT3 activation during hepatocarcinogenesis induced by neonatal diethylnitrosamine (DEN) treatment in mice. Nuclear accumulation and phosphorylation of STAT3 were detected in altered hepatocyte foci in the
Marta Anna Kowalik et al.
Oncotarget, 6(36), 38749-38763 (2015-10-10)
Although the expression of the stem/progenitor cell marker cytokeratin-19 (CK-19) has been associated with the worst clinical prognosis among all HCC subclasses, it is yet unknown whether its presence in HCC is the result of clonal expansion of hepatic progenitor
Takeki Uehara et al.
Toxicological sciences : an official journal of the Society of Toxicology, 132(1), 53-63 (2013-01-05)
Hepatocellular carcinoma (HCC) mostly develops in patients with advanced fibrosis; however, the mechanisms of interaction between a genotoxic insult and fibrogenesis are not well understood. This study tested a hypothesis that fibrosis promotes HCC via a mechanism that involves activation
L Verna et al.
Pharmacology & therapeutics, 71(1-2), 57-81 (1996-01-01)
N-Nitrosodiethylamine (NDEA) is DNA reactive after bioactivation and produces tumors in every animal species tested. Bioactivation is effected by several P450 isozymes including CYP2E1, which is ethanol inducible. Tumor formation in rat liver was proportional to O4-ethyldeoxythymidine formation in DNA
Michael T Dill et al.
Hepatology (Baltimore, Md.), 57(4), 1607-1619 (2012-11-24)
Hepatocellular carcinoma (HCC) and cholangiocarcinoma (CCC) are the most common liver tumors and a leading cause for cancer-related death in men. Notch2 regulates cellular differentiation in the developing and adult liver. Although aberrant Notch signaling is implicated in various cancers

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