V5390

VU0029251

≥98% (HPLC), powder

• 别名: 6,7-Dihydro-2-(methylthio)-5H-cyclopenta[4,5]thieno[2,3-d]pyrimidin-4-amine
• 经验公式（希尔记法）: C₁₀H₁₁N₃S₂
• 分子量: 237.34
• MDL號碼: MFCD00698485
• 分類程式碼代碼: 12352200
• PubChem物質ID: 329829058
• NACRES: NA.77

属性

• 化驗: ≥98% (HPLC)
• 形狀: powder
• 顏色: white to tan
• 溶解度: DMSO: ≥11 mg/mL
• 儲存溫度: 2-8°C
• SMILES 字串: CSc1nc(N)c2c3CCCc3sc2n1
• InChI: 1S/C10H11N3S2/c1-14-10-12-8(11)7-5-3-2-4-6(5)15-9(7)13-10/h2-4H2,1H3,(H2,11,12,13)
• InChI 密鑰: WDDBZCKBRCTSOZ-UHFFFAOYSA-N

说明

生化／生理作用

VU0029251 is the first example of a partial mGluR5 partial antagonist that is not based on the MPEP scaffold. The compound displays a maximum inhibition of 50% activity, and cannot completely displace [3H] MPEP, suggesting that competition for MPEP is also allosteric, involving a unique site.

特點和優勢

This compound is featured on the Glutamate Receptors (G Protein Family) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

安全信息

• 儲存類別代碼: 13 - Non Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable