T0953
14-3-3 Tau/Theta histidine-tagged human
recombinant, expressed in E. coli, C-terminal, ≥90% (SDS-PAGE), buffered aqueous glycerol solution
别名:
14-3-3 tau, 14-3-3 theta, 14-3-3t, 1C5, Bap1, HS1, Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide, YWHAQ
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About This Item
重組細胞
expressed in E. coli
品質等級
化驗
≥90% (SDS-PAGE)
形狀
buffered aqueous glycerol solution
分子量
~30 kDa (14-3-3 proteins)
UniProt登錄號
運輸包裝
dry ice
儲存溫度
−20°C
基因資訊
human ... YWHAQ(10971)
生化/生理作用
14-3-3 proteins are involved in a multitude of biological processes and play a regulatory role in processes such as apoptotic cell death, mitogenic signal transduction, and cell cycle control. Co-immunoprecipitation experiments demonstrate the interaction of 14-3-3 τ/θ adaptor protein with various proteins (UCP3, PKCζ). 14-3-3 τ/θ is involved in cell cycle arrest and cellular differentiation. 14-3-3 τ/θ plays an active role in mediating Vpr-induced cell cycle arrest in human T cells.
外觀
Supplied as a 0.2 μm filtered solution in 50 mM Tris-HCl, pH 7.6, 1 mM EDTA, 1 mM DTT, and 20% glycerol (w/v).
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产品编号
说明
价格
儲存類別代碼
10 - Combustible liquids
水污染物質分類(WGK)
WGK 1
閃點(°F)
Not applicable
閃點(°C)
Not applicable
個人防護裝備
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
Mathematical biology in Biology Direct.
Biology direct, 3, 1-1 (2008-01-18)
14-3-3 isotypes facilitate coupling of protein kinase Cζ to Raf-1: negative regulation by 14-3-3 phosphorylation.
The Biochemical Journal, 15, 297-306 (2000)
European journal of biochemistry, 267(9), 2680-2687 (2000-04-28)
Uncoupling proteins (UCPs) are members of the superfamily of the mitochondrial anion carrier proteins (MATP). Localized in the inner membrane of the organelle, they are postulated to be regulators of mitochondrial uncoupling. UCP2 and 3 may play an important role
Molecular & cellular proteomics : MCP, 7(7), 1225-1240 (2008-04-02)
The 14-3-3 proteins constitute a family of highly conserved and broadly expressed multifunctional polypeptides that are involved in a variety of important cellular processes that include cell cycle progression, growth, differentiation, and apoptosis. Although the exact cellular function(s) of 14-3-3
14-3-3 proteins: active cofactors in cellular regulation by serine/threonine phosphorylation.
The Journal of biological chemistry, 277(5), 3061-3064 (2001-11-16)
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