T0283

Calcitonin rat

≥95% (HPLC), powder

• 别名: Thyrocalcitonin
• 经验公式（希尔记法）: C₁₄₈H₂₂₈N₄₀O₄₆S₃
• CAS号: 11118-25-5
• 分子量: 3399.83
• MDL编号: MFCD00133857
• UNSPSC代码: 51111800
• PubChem化学物质编号: 24899879

属性

• 方案: ≥95% (HPLC)
• 表单: powder
• UniProt登记号: P01257; P01256
• 储存温度: −20°C
• SMILES字符串: CCC(C)C(NC(=O)C(CO)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C1CCCN1C(=O)C(Cc2ccccc2)NC(=O)C(NC(=O)C(Cc3cnc[nH]3)NC(=O)C(Cc4ccccc4)NC(=O)C(CCCCN)NC(=O)C(CC(N)=O)NC(=O)C(CC(C)C)NC(=O)C(CC(O)=O)NC(=O)C(CCC(N)=O)NC(=O)C(NC(=O)C(Cc5ccc(O)cc5)NC(=O)C(NC(=O)CNC(=O)C(CC(C)C)NC(=O)C(CCSC)NC(=O)C6CSSCC(N)C(=O)NCC(=O)NC(CC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CO)C(=O)NC(C(C)O)C(=O)N6)C(C)O)C(C)O)C(C)O)C(C)O)C(=O)NCC(=O)NC(C(C)C)C(=O)NCC(=O)NC(C)C(=O)N7CCCC7C(N)=O
• 基因信息: rat ... Calca(24241)

说明

Amino Acid Sequence

Cys-Gly-Asn-Leu-Ser-Thr-Cys-Met-Leu-Gly-Thr-Tyr-Thr-Gln-Asp-Leu-Asn-Lys-Phe-His-Thr-Phe-Pro-Gln-Thr-Ser-Ile-Gly-Val-Gly-Ala-Pro-NH₂ [Disulfide Bridge: 1-7]

生化/生理作用

Hypocalcemic hormone produced by the parafollicular C cells of the thyroid or by the ultimobranchial bodies of nonmammalian vertebrates. Decreases blood calcium and phosphate due to inhibition of resorption by osteoblasts and osteocytes.

其他说明

32 amino acid polypeptide, 8 of which are conserved across all species.

安全信息

• 储存分类代码: 13 - Non Combustible Solids
• WGK: WGK 3
• 闪点(°F): Not applicable
• 闪点(°C): Not applicable
• 个人防护装备: Eyeshields, Gloves, type N95 (US)