跳转至内容
Merck
所有图片(1)

主要文件

SRP6309

Sigma-Aldrich

Proteinase 3 from human neutrophils

≥95% (SDS-PAGE)

别名:

AGP7, C-ANCA antigen, Leukocyte proteinase 3, Neutrophil proteinase 4, P29, Wegener autoantigen

登录查看公司和协议定价


About This Item

分類程式碼代碼:
12352200

生物源

human

化驗

≥95% (SDS-PAGE)

形狀

frozen liquid

分子量

29 kDa

包裝

pkg of 25 μg

UniProt登錄號

運輸包裝

dry ice

儲存溫度

−70°C

基因資訊

human ... AGP7(5657)

一般說明

Proteinase 3 is one of the serine proteinases localized in azurophil granules of polymorphonuclear leukocytes. It has been identified as the autoantigen of Wegener granulomatosis, a systemic vasculitis complicated by melomonocyte proliferation. It exhibits proteolytic activity towards a range of substrates. It is physiologically inhibited by α1-antitrypsin. The protein has been described as having antibiotic and growth-promoting properties and causing emphysema when administered by tracheal insufflation. Proteinase 3 (PR-3) is also known as myeloblastin and p29b.

外觀

Frozen in 50 mM MES, pH 4.5 with 700 mM NaCl.

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

nwg

閃點(°F)

Not applicable

閃點(°C)

Not applicable


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

没有发现合适的版本?

如果您需要特殊版本,可通过批号或批次号查找具体证书。

已有该产品?

在文件库中查找您最近购买产品的文档。

访问文档库

其他客户在看

Slide 1 of 1

1 of 1

Jeppe Thorlacius-Ussing et al.
Journal of cancer research and clinical oncology, 145(2), 383-392 (2018-11-24)
Elastin is a signature protein of lungs. Increased elastin turnover driven by altered proteolytic activity is an important part of lung tumorigenesis. Elastin-derived fragments have been shown to be pro-tumorigenic, however, little is known regarding the biomarker potential of such
Luis M Molinos-Albert et al.
Nature communications, 13(1), 1944-1944 (2022-04-13)
HIV-1 post-treatment controllers are rare individuals controlling HIV-1 infection for years after antiretroviral therapy interruption. Identification of immune correlates of control in post-treatment controllers could aid in designing effective HIV-1 vaccine and remission strategies. Here, we perform comprehensive immunoprofiling of

我们的科学家团队拥有各种研究领域经验,包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系客户支持