生物源
human
重組細胞
expressed in baculovirus infected Sf9 cells
化驗
≥90% (SDS-PAGE)
形狀
aqueous solution
分子量
37.5 kDa
包裝
pkg of 100 μg
NCBI登錄號
UniProt登錄號
運輸包裝
dry ice
儲存溫度
−70°C
基因資訊
human ... WDR5(11091)
一般說明
Human WDR5 (WD Repeat Domain 5), also known as SWD3 or BIG-3 (GenBank Accession No. NM_017588) amino acids 2-334 (end) with N-terminal His-tag, MW=37.5 kDa, expressed in Sf9 insect cells via a Baculovirus expression system.
應用
Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
訊號詞
Danger
危險聲明
危險分類
Eye Irrit. 2 - Repr. 1B - Skin Irrit. 2
儲存類別代碼
6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
水污染物質分類（WGK）
WGK 1
閃點（°F）
Not applicable
閃點（°C）
Not applicable
WDR5, a complexed protein.
Raymond C Trievel et al.
Nature structural & molecular biology, 16(7), 678-680 (2009-07-07)
Yan-Yi Wang et al.
Proceedings of the National Academy of Sciences of the United States of America, 107(2), 815-820 (2010-01-19)
Viral infection causes activation of the transcription factors NF-kappaB and IRF3, which collaborate to induce type I interferons (IFNs) and cellular antiviral response. The mitochondrial outer membrane protein VISA acts as a critical adapter for assembling a virus-induced complex that
Zain Odho et al.
The Journal of biological chemistry, 285(43), 32967-32976 (2010-08-19)
Histone modification is well established as a fundamental mechanism driving the regulation of transcription, replication, and DNA repair through the control of chromatin structure. Likewise, it is apparent that incorrect targeting of histone modifications contributes to misregulated gene expression and
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