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Merck
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文件

SRP0348

Sigma-Aldrich

Flt1 active human

recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE)

别名:

VEGFR1, fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)

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About This Item

分類程式碼代碼:
12352200
NACRES:
NA.32

生物源

human

重組細胞

expressed in baculovirus infected Sf9 cells

化驗

≥70% (SDS-PAGE)

形狀

aqueous solution

分子量

67.5 kDa

包裝

pkg of 10 μg

技術

activity assay: suitable
inhibition assay: suitable

NCBI登錄號

AF063657

UniProt登錄號

P17948

運輸包裝

dry ice

儲存溫度

−70°C

基因資訊

human ... FLT1(2321)

一般說明

Human Flt1 ( GenBank Accession No. AF063657), amino acids 783-end with N-terminal His-tag, MW=67.5 kDa, expressed in a Baculovirus infected Sf9 cell expression system.

應用

Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.

單位定義

One unit is defined as the amount of enzyme that will transfer 1 nmol phosphate to the tyrosine substrate per minute at pH 7.4 and 30°C.

象形圖

Health hazardExclamation mark
GHS08,GHS07

訊號詞

Danger

危險聲明

H315,H319,H360D

危險分類

Eye Irrit. 2 - Repr. 1B - Skin Irrit. 2

儲存類別代碼

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

水污染物質分類（WGK）

WGK 1

閃點（°F）

Not applicable

閃點（°C）

Not applicable

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M Shibuya
The international journal of biochemistry & cell biology, 33(4), 409-420 (2001-04-20)
Vascular endothelial growth factor receptor-1 (VEGFR-1/Flt-1) is structurally a typical tyrosine kinase receptor of about 180 kDa, and carries seven Ig-like domains in the extracellular region and a tyrosine kinase domain with a long kinase insert. Recent studies have revealed
N Rahimi et al.
The Journal of biological chemistry, 275(22), 16986-16992 (2000-04-05)
Vascular endothelial growth factor (VEGF) provokes angiogenesis in vivo and stimulates growth and differentiation of endothelial cells in vitro. Although VEGF receptor-1 (VEGFR-1) and VEGFR-2 are known to be high affinity receptors for VEGF, it is not clear which of

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