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Ganoderic acid D is one of major triterpenes isolated from Ganoderma lucidum that exhibit potent anticancer properties. Ganoderic acid D inhibits the energy reprogramming of colon cancer cells including glucose uptake, lactate, and pyruvate and acetyl-coenzyme production through SIRT3 upregulation via acetylated cyclophilin D inhibition.
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
Zhendong Liu et al.
European journal of pharmacology, 824, 72-77 (2018-01-29)
Ganoderic acid D (GAD) is a highly oxygenated tetracyclic triterpenoid. This study aims to assess the effects of GAD on the energy metabolism of colon cancer through the regulation of SIRT3 expression and whether this effect is related to acetylated
Ruo-Lin Zhao et al.
Journal of ethnopharmacology, 210, 287-295 (2017-09-09)
Ganoderma lucidum (GL) is an oriental medical fungus, which was used to prevent and treat many diseases. Previously, the effective compounds of Ganoderma lucidum extract (GLE) were extracted from two kinds of GL, [Ganoderma lucidum (Leyss. Ex Fr.) Karst.] and
Qing-Xi Yue et al.
Molecular & cellular proteomics : MCP, 7(5), 949-961 (2008-01-02)
Triterpenes isolated from Ganoderma lucidum could inhibit the growth of numerous cancer cell lines and were thought to be the basis of the anticancer effects of G. lucidum. Ganoderic acid D (GAD) is one of the major components in Ganoderma
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