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Brain-permeable, potent and selective EP2 receptor antagonist
TG11-77 is a brain-permeable, water soluble, highly potent, and selective EP2 receptor antagonist. TG11-77 suppress inflammatory gene expression induced by EP2 activation in a microglial cell line. TG11-77 is useful for study CNS diseases in rodent models.
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
历史批次信息供参考:
Potent, selective, water soluble, brain-permeable EP2 receptor antagonist for use in central nervous system disease models.
Radhika Amaradhi, et al.
Journal of Medicinal Chemistry, 63(3), 1032-1050 (2020)
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