SML2987
Cefcapene Pivoxil Hydrochloride Hydrate
≥98% (HPLC)
别名:
Cefcapene Pivoxil Hydrochloride Hydrate, [6R-[6α,7β(Z)]]-3-[[(Aminocarbonyl)oxy]methyl]-7-[[2-(2-amino-4-thiazolyl)-1-oxo-2-pentenyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid (2,2-dimethyl-1-oxopropoxy)methyl ester monohydrochloride monohydrate
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About This Item
经验公式（希尔记法）:
C23H29N5O8S2 · xHCl · yH2O
分子量:
567.64 (anhydrous free base basis)
UNSPSC代码:
12352200
NACRES:
NA.77
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生化/生理作用
Cefcapene Pivoxil Hydrochloride Hydrate is an orally available prodrug of third-generation cephalosporin cefcapene that exhibits potent and wide spectrum antibacterial activity against Gram-positive and Gram-negative bacteria, including Staphylococcus aureus.
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
历史批次信息供参考:
Masamoto Murakami et al.
Dermatology (Basel, Switzerland), 231(4), 304-311 (2015-10-07)
Pustulosis palmaris et plantaris or palmoplantar pustulosis (PPP) is a refractory pustular eruption of the palms and soles with unknown etiology. In addition to skin lesions, PPP patients may present with severe joint pain and pustulotic arthro-osteitis (PAO), especially of
Przemysław Zalewski et al.
Chromatographia, 76(7-8), 387-391 (2013-04-05)
The stability-indicating LC assay method was developed and validated for quantitative determination of cefcapene pivoxil in the presence of degradation products formed during forced degradation studies. An isocratic RP-HPLC method was developed with a Lichrospher RP-18 (250 mm × 4.6 mm, 5 μm) column and
Xin He et al.
Antimicrobial agents and chemotherapy, 48(7), 2604-2609 (2004-06-25)
The aim of this study was to elucidate the absorption mechanism in Caco-2 and rat intestine models in order to improve the accuracy of prediction of oral absorption of ester prodrugs. Pivampicillin and cefcapene pivoxil hydrochloride (CFPN-PI), ester-type oral antibiotics
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