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化驗
≥98% (HPLC)
形狀
powder
儲存條件
desiccated
顏色
white to dark gray
溶解度
DMSO: 2 mg/mL, clear
儲存溫度
2-8°C
生化／生理作用
Intronistat B is a potent inhibitor of the self-splicing group IIB intron, a mitochondrial RNA tertiary structure necessary for respiration in fungi, yeast and plants, but not found in vertebrates. Intronistat B was found to have antifungal activity comparable to that of amphotericin B in inhibiting growth of the Candida parapsilosis. It did not inhibit spliceosomal processing, group I intron splicing or splicing of group II introns from subclasses other than subclass IIB and was not toxic to human cells.
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
Olga Fedorova et al.
Nature chemical biology, 14(12), 1073-1078 (2018-10-17)
Specific RNA structures control numerous metabolic processes that impact human health, and yet efforts to target RNA structures de novo have been limited. In eukaryotes, the self-splicing group II intron is a mitochondrial RNA tertiary structure that is absent in
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