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Merck
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SML2110

Sigma-Aldrich

WOBE437

≥98% (HPLC)

别名:

(2E,4E)-N-[2-(3,4-Dimethoxyphenyl)ethyl]dodeca-2,4-dienamide

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About This Item

经验公式（希尔记法）:
C22H33NO3
CAS号:
2108100-73-6
分子量:
359.50
UNSPSC代码:
12352200
NACRES:
NA.77

方案

≥98% (HPLC)

表单

powder

颜色

white to beige

溶解性

DMSO: 2 mg/mL, clear

储存温度

2-8°C

SMILES字符串

CCCCCCC/C=C/C=C/C(NCCC1=CC(OC)=C(OC)C=C1)=O

InChI

1S/C22H33NO3/c1-4-5-6-7-8-9-10-11-12-13-22(24)23-17-16-19-14-15-20(25-2)21(18-19)26-3/h10-15,18H,4-9,16-17H2,1-3H3,(H,23,24)/b11-10+,13-12+

InChI key

LAHLFCSEHHJQRN-AQASXUMVSA-N

生化/生理作用

WOBE437 is a highly potent and selective endocannabinoid transport inhibitor. WOBE437 increases endocannabinoid levels in mice. It exhibits potent anxiolytic, anti-inflammatory, and analgesic effects in mice.
highly potent and selective endocannabinoid transport inhibitor

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
0000102298
0000102299
0000098209

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Andrea Chicca et al.
Proceedings of the National Academy of Sciences of the United States of America, 114(25), E5006-E5015 (2017-06-07)
The extracellular effects of the endocannabinoids anandamide and 2-arachidonoyl glycerol are terminated by enzymatic hydrolysis after crossing cellular membranes by facilitated diffusion. The lack of potent and selective inhibitors for endocannabinoid transport has prevented the molecular characterization of this process

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