SML1211

SMANT hydrochloride

≥98% (HPLC)

• 别名: N-(4-Bromophenyl)-3-(3,5-dimethylpiperidin-1-yl)propanamide hydrochloride
• 经验公式（希尔记法）: C₁₆H₂₃BrN₂O · HCl
• CAS号: 1177600-74-6
• 分子量: 375.73
• MDL號碼: MFCD06620515
• 分類程式碼代碼: 51111800
• PubChem物質ID: 329825721
• NACRES: NA.77

属性

• 化驗: ≥98% (HPLC)
• 形狀: powder
• 儲存條件: desiccated
• 顏色: white to beige
• 溶解度: H₂O: 1 mg/mL, clear (warmed)
• 儲存溫度: 2-8°C
• SMILES 字串: BrC1=CC=C(NC(CCN2CC(C)CC(C)C2)=O)C=C1.Cl
• InChI: 1S/C16H23BrN2O.ClH/c1-12-9-13(2)11-19(10-12)8-7-16(20)18-15-5-3-14(17)4-6-15;/h3-6,12-13H,7-11H2,1-2H3,(H,18,20);1H
• InChI 密鑰: XQESCHFXROUCOQ-UHFFFAOYSA-N

说明

生化／生理作用

SMANT is a Hedgehog pathway antagonist, a Smoothened antagonist that behaves similarly against normal cancer smoothened and the M2 mutant. In a study comparing activities among the currently known smoothened/Hedgehog antagonists, SMANT behaves differently, binding to another Smo site different to that bound by other compounds.

安全信息

• 象形圖: GHS09
• 危險聲明: H411
• 防範說明: P273 - P391 - P501
• 危險分類: Aquatic Chronic 2
• 儲存類別代碼: 13 - Non Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable