SML0983

5F-203

≥98% (HPLC)

• 别名: 4-(5-Fluoro-2-benzothiazolyl)-2-methyl-benzenamine, 5F203, NSC-703786
• 经验公式（希尔记法）: C₁₄H₁₁FN₂S
• CAS号: 260443-89-8
• 分子量: 258.31
• 分類程式碼代碼: 12352200
• NACRES: NA.77

属性

• 品質等級: 100
• 化驗: ≥98% (HPLC)
• 形狀: powder
• 顏色: white to beige
• 溶解度: DMSO: 20 mg/mL, clear
• 儲存溫度: 2-8°C
• SMILES 字串: Fc1cc2nc([s]c2cc1)c3cc(c(cc3)N)C
• InChI: 1S/C14H11FN2S/c1-8-6-9(2-4-11(8)16)14-17-12-7-10(15)3-5-13(12)18-14/h2-7H,16H2,1H3
• InChI 密鑰: IFWLHIIUGSEKKE-UHFFFAOYSA-N

说明

生化／生理作用

5F-203 is a cytotoxic molecule that forms DNA adducts that lead to cell death.

5F-203 is a cytotoxic molecule that forms DNA adducts that lead to cell death. 5F-203 induces aryl hydrocarbon receptor signaling, and elevates expression of CYP1A1. Treatment of cells with 5F-203 also leads to elevation of reactive oxygen species and activation of p38, JNK and ERK.

特點和優勢

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安全信息

• 象形圖: GHS07
• 訊號詞: Warning
• 危險聲明: H302
• 防範說明: P264 - P270 - P301 + P312 - P501
• 危險分類: Acute Tox. 4 Oral
• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable